Study of Some Psychoactive Drugs and Their Role in Increasing the Risk of Suicide

Abstract

The study aims to evaluate some predictors in the statement of suicidal thoughts in the last year by students from Timisoara universities, Romania. The student population consisted of 2536 young people aged 18-29, with an average age of 21.06 years and a standard deviation of 1.529 years, 64.5% girls and 35.5% boys. It was conducted a transversal population survey. In the logarithmic model of predictors in the context of social and psychoactive drugs use in students regarding the likelihood of suicidal thoughts in the last year, we have identified predictors with OR between 1.5-2, poorly significant: dissatisfaction with the relationship with parents (OR = 1.782), drug use frequency (OR = 1.697), dissatisfaction with the relationship with current friends (OR = 1.531).

Use of psychoactive substances by young people reporting suicidal thoughts, plans, and attempts in the context of sociodemographic factors

“…According to Gauthier et al [7], alcohol abuse is a risk factor for suicidal ideation in this group of people. Such results also appeared in the latest international studies [15,19,[25][26][27].…”

Cinnarizine - Potential Trigger of the Dopamine Supersensitivity Psychosis in Patients with Paranoid Schizophrenia Particular neurobiochemical model

“…In the accumbens nucleus, unbalancing the ratio between D2 and D3 receptors causes depression and addictive tendencies, making a real reward disorder pathology [30]. Simultaneously, the same imbalance amplifies the disconnectivity of cerebral amygdale, especially at the level of the basolateral nuclear complex, favoring the emergence of social behavioral disorders manifested through aggression, violence, suicide [31][32][33]. In animals it has been described an aberrant type of a global talamo-cortical connection that could represent the neurobiological model for the appearance of tinnitus in patients with schizophrenia [34,35] .…”