Activation processes in a nuclear power plant are mainly due to neutron reactions. The determination of the neutron fluences in the reactor pressure vessel (RPV) is therefore the main task of the reactor dosimetry and the good experience for the activity evaluation has to be used. From 2005 to 2009 trepans were gained from the RPV of decommissioned nuclear power plant in Greifswald for the embrittlement investigation. For the first time, samples could be taken from the inner part of the RPV and activity measurements were performed. Experimental results were obtained for