Study of the Effect of Three Extraction Processes on the Phytoactives of Alchornea cordifolia (Schumach. & Thonn.) Müll. Arg. (Euphorbiaceae) and Evaluation of their Antioxidant and Analgesic Activities

Abstract

Aims: An important aspect of the valorization of plants of interest is the search for phytoactives. This work aims to show the effect of extractive processes (maceration, decoction, Soxhlet extraction) both on the phytoconstituents of a plant species and on their intrinsic properties.
 Methodology: Alchornea cordifolia, a botanical species growing in Côte d'Ivoire, was chosen for this purpose. Phytophenols, flavonoids and condensed tannins were quantified by spectrophotometry. Antioxidant (DPPH and FRAP) and analgesic activity were also evaluated.
 Results: The quantitative analysis of total phytophenols, total flavonoids and condensed tannins of macerated, decocted and Soxhlet extracts of the plant organs (leaves, stems, roots), highlighted their respective contents, varying proportionally according to the extraction conditions. The same observation was made at the end of the estimation of the antioxidant (DPPH and FRAP tests) and analgesic activities of these different extraction fractions.
 Conclusion: This study has demonstrated the effect of three extraction processes on some phytoactives quantified of A. cordifolia.

Effect of individual factors on the extraction of phenolic compounds from turmeric rhizomes (Curcuma longa) and moringa leaves (Moringa oleifera

“…However, the extraction of these phenolic compounds remains problematic as it differs from one plant to another and is strongly influenced by several factors [3,18].…”

“…Furthermore, in this age of advances in organic chemistry, it is clear that more than 25% of medicines prescribed in industrialised countries derive their active ingredients directly or indirectly from plants [2]. These therapeutic effects are due to the bioactive compounds present in plants, such as polyphenols, flavonoids and tannins [1,2,3]. These are natural antioxidants that are attracting increasing interest for their potential use in the prevention and treatment of inflammatory and metabolic diseases such as diabetes, hypertension and obesity.…”

“…However, in traditional Ivorian medicine, the extraction of these bioactive compounds is often carried out without taking into account the various factors involved in the process. These include the drying time of the plant matrix, the particle size of the powder, the solvent concentration, the ratio of material/solvent, the speed, the temperature and the extraction time [3,13,14]. These factors, which come into play during the various conventional extraction processes (maceration, infusion and decoction) and which are not taken into account, affect the food or therapeutic quality of the extracts [3,15].…”

“…These include the drying time of the plant matrix, the particle size of the powder, the solvent concentration, the ratio of material/solvent, the speed, the temperature and the extraction time [3,13,14]. These factors, which come into play during the various conventional extraction processes (maceration, infusion and decoction) and which are not taken into account, affect the food or therapeutic quality of the extracts [3,15]. Thus, the general aim of this work is to assess the influence of seven factors involved in the process of extracting phenolic compounds from Curcuma longa rhizomes and Moringa oleifera leaves.…”