Study of the Effect of Hydrophilic Gel Contact Lenses on the Cornea

Influence of Soft Contact Lens Solutions on Rabbit Corneae

“…Therefore, the corneal metabolism was disturbed, and we did find slight epithelial alterations in the control eyes. As to oxygen consumption by the corneal epithelium beneath a permanently fixed soft contact lens, it is raised only during the first week; the following days it dropped to almost the normal level (11,18,13). In the fluid-tested eyes, we found a significantly higher degree of epithelial, stromal, and even endothelial damage, as described before.…”

Interactions between Ocular Surface Fluid and Cornea Related to Contact Lenses

“…4). These results indicated that minimal surface trauma may be assessed from these physiological and biochemical parameters (21,(24)(25)(26)(27)(28)(29). Another small alteration of the corneal surface was observed during simple rinsing with saline.…”

“…Different lens types and materials induced highly variable increases. Corneal hydration is defined as H = wet -dry weight/dry weight(21,(24)(25)(26)(27)(28)(29).Lactate levels of cornea under contact lenses % increase over normal values Lactate levels in the cornea under various contact lenses. The levels increased during contact lens wear, like hydration shown inFigure 3 (21, 24-29).…”

Hydrophilic Contact Lenses ‐ Their Effect on the Cornea

“…Masnick (1971) found that "Hyd ron" lenses caused significantly less keratometric change than conventional hard lenses. The absence of any oedematous change has been claimed by Kaufman and Gasset (1969) and Williams (1970), and by Praus, Brettschneider and Dreifus (1969), who fitted "Geltakt" lenses to rabbits. On the other hand, Bennett has cited Mandell (1970) as describing an overall corneal thickness change following hydrophilic lens wear.…”