Study of the formation of the open-cellular morphology of poly(styrene/divinylbenzene) polyHIPE materials by cryo-SEM

Cameron, Neil R.; Sherrington, D. C.; Albiston, L.; Gregory, D.P.

doi:10.1007/bf00655236

Cited by 290 publications

(318 citation statements)

References 4 publications

Supporting

Mentioning

307

Contrasting

Unclassified

Order By: Relevance

“…Emulsion templating is a convenient method to prepare highly porous polymeric materials with well-defined morphology [1][2][3][4][5][6] . The process involves preparing a high internal phase emulsion (HIPE), i.e.…”

Section: Introductionmentioning

confidence: 99%

“…This increases the range of precursor materials available for polyHIPE preparation. In previous work we demonstrated that thiol-ene and thiol-yne photopolymerisation, 4 employing commercially available multifunctional thiols with either multifunctional acrylates or alkynes, can also be employed for the preparation of polyHIPE materials 32 . These methods yield well-defined thiol-ene/yne network polyHIPE materials with mechanical properties dependent on the extent of crosslinking.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Degradable emulsion-templated scaffolds for tissue engineering from thiol–ene photopolymerisation

et al. 2012

View full text Add to dashboard Cite

Further information on publisher's website:http://dx.doi.org/10.1039/c2sm26250aPublisher's copyright statement:Additional information: Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. AbstractEmulsion templating has been used to prepare highly porous polyHIPE materials by thiol-ene photoinitiated network formation. Commercially available multifunctional thiols and acrylates were formulated into water-in-oil high internal phase emulsions (HIPEs) using an appropriate surfactant, and the HIPEs were photo-cured. The temperature of the HIPE aqueous phase was found to influence the morphology of the resulting materials. In agreement with previous work, a higher aqueous phase temperature (80 o C) gave rise to a larger mean void and interconnect diameter. The influence of temperature on morphology was found to be reduced at higher porosity, but still significant. The Young's modulus of the porous materials was shown to be related to the functionality of the acrylate comonomer used. A mixture of penta-and hexa-acrylate gave rise to a 100-fold increase in modulus, compared to an analogous tri-functional acrylate. The materials could be functionalised conveniently by addition of mono-acrylates or thiols to the organic phase of the precursor HIPE. Degradation was observed to occur at a rate depending on the degradation conditions. Under cell culture conditions at 37 o C, 19% mass loss occurred over 15 weeks. The scaffolds were found to be capable of supporting the growth of keratinocytic cells (HaCaTs) over 11 days in culture. Some penetrative in-growth of the cells into the scaffold was observed.3

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Degradable emulsion-templated scaffolds for tissue engineering from thiol–ene photopolymerisation

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Initially developed by Unilever 16 , polyHIPE preparation traditionally involves the formation of a stable concentred water-in-oil emulsion using hydrophopic monomers as part of the continuous phase and an aqueous phase as the dispersed phase. 17,18 Introducing a homogeneous, highly dense layer of functional groups available for bioconjugation to the macroporous surface is essential to advance polyHIPE applications in areas biosensing and biosepara-tion. Currently only few publications discuss the modification of polyHIPE surfaces with polymer brushes.…”

Section: Introductionmentioning

confidence: 99%

Protein Immobilization onto Poly(acrylic acid) Functional Macroporous PolyHIPE Obtained by Surface-Initiated ARGET ATRP

et al. 2012

View full text Add to dashboard Cite

Amino-functional macroporous monoliths from polymerized high internal phase emulsion (polyHIPE) were surface modified with initiators for atom transfer radical polymerization (ATRP). The ATRP initiator groups on the polyHIPE surface were successfully used to initiate activator regeneration by electron transfer (ARGET) ATRP of (meth)acrylic monomers, such as methyl methacrylate (MMA) or tert-butyl acrylate (tBA) resulting in a dense coating of polymers on the polyHIPE surface. Addition of sacrificial initiator permitted control of the amount of polymer grafted onto the monolith surface. Subsequent removal of the tertbutyl protecting groups yielded highly functional polyHIPE-g-poly(acrylic acid). The versatility to use the high density of carboxylic acid groups for secondary reactions was demonstrated by the successful conjugation of enhanced green fluorescent protein (eGFP) and coral derived red fluorescent protein (DsRed) using EDC/sulfo-NHS chemistry, on the polymer 3D-scaffold surface. The materials and methodologies presented here are simple and robust, thus, opening new possibilities for the bioconjugation of highly porous polyHIPE for bioseparation applications.

show abstract

“…This phenomenon resulted from the fact that the more stable emulsion, the smaller droplets and more droplets. So that the concentration of surfactant(Tween 60), considered as porogen for formation of interconnect pore [8], in each droplet decreased, which caused the decreasing of the average interconnecting pore diameter and the interconnectivity degree (Fig.2). , 5) showed that when the concentration of Tween 60 in the aqueous phase increased, the void diameter and interconnecting pore diameter decreased, and the interconnectivity increased.…”

Section: Resultsmentioning

confidence: 99%

Porous Poly(Acrylic Acid) from High Internal Phase Emulsion: Effects of Emulsification Parameters on Porous Structure

et al. 2016

View full text Add to dashboard Cite

Abstract. Highly porous poly (acrylic acid) (P(AA)) with tunable pore structure was prepared through polymerizing of acrylic acid in the aqueous phase of an oil-in-water (O/W) high internal phase emulsion (HIPE). Compared with the conventional O/W HIPE normally using toluene or hexane as internal phase, the introducing paraffin, which have a much higher viscosity than toluene or hexane, caused the HIPEs herein could be stabilized by Tween 60 of low to 0.5 wt%. It was found the amount of liquid paraffin played a key role for the stability of the emulsion and the morphology of the resulting porous materials. Moreover, the average void size and the interconnectivity degree of the porous materials could also be tailored by altering the acrylic acid and surfactant concentration in aqueous phase.

show abstract

Study of the formation of the open-cellular morphology of poly(styrene/divinylbenzene) polyHIPE materials by cryo-SEM

Cited by 290 publications

References 4 publications

Degradable emulsion-templated scaffolds for tissue engineering from thiol–ene photopolymerisation

Degradable emulsion-templated scaffolds for tissue engineering from thiol–ene photopolymerisation

Protein Immobilization onto Poly(acrylic acid) Functional Macroporous PolyHIPE Obtained by Surface-Initiated ARGET ATRP

Porous Poly(Acrylic Acid) from High Internal Phase Emulsion: Effects of Emulsification Parameters on Porous Structure

Contact Info

Product

Resources

About