Study of the Operability of Nonideal Continuous Bioreactors

Ajbar, Abdelhamid

doi:10.1080/00986445.2010.512544

Cited by 4 publications

(1 citation statement)

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“…In‐depth study of the deviation of behavior of a bioreactor from the ideal due to continuous growth of biomass in the system is one such area. Unlike conventional chemical reactors, the extent of non‐ideality of bioreactors is enhanced due to the increase in viscosity with growth of biomass in the reactor . Although this is a serious drawback to considering a chemostat an ideal reactor, studies on hydro‐dynamic behavior of bioreactors and development of hydraulic modeling of bioreactors are not very often reported in the literature.…”

Section: Introductionmentioning

confidence: 99%

Mathematical modelling of ideal and non‐ideal continuous stirred tank bioreactor using simulated solution

Sarkar

Chowdhury

Mukherjee

2014

J of Chemical Tech & Biotech

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Section: Introductionmentioning

confidence: 99%

Mathematical modelling of ideal and non‐ideal continuous stirred tank bioreactor using simulated solution

Sarkar

Chowdhury

Mukherjee

2014

J of Chemical Tech & Biotech

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Steady-state analysis of activated sludge processes with a settler model including sludge compression

2016

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Analysis of a Chemostat Model with Variable Yield Coefficient and Substrate Inhibition: Contois Growth Kinetics

Alqahtani

Nelson

Worthy

2014

Chemical Engineering Communications

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2015, Copyright Taylor & Francis Group, LLC.We analyze the steady-state operation of a generalized reactor model that encompasses a continuous flow bioreactor and an idealized continuous flow membrane reactor as limiting cases. The biochemical reaction kinetics is governed by a Contois growth model subject to noncompetitive substrate inhibition with a variable substrate yield coefficient. The steady-state performance of the reactor is predicted and stability of the steady-state solutions as a function of dimensionless residence time reported. Our results identified two cases of practical interest. The first feature corresponds to the case where solutions to both no-washout and washout conditions are bistable. The second feature identifies the parameter region in which periodic solutions can occur when the yield coefficient is not constant. Both these features are often undesirable in practical applications and must be avoided. Scaling of the model equations reveals that both the second-bifurcation parameters are functions of the influent concentration. Our results predict how the reactor behavior varies as a function of influent concentration and identify the range of influent concentrations where the reactor displays neither periodic nor bistable behavior.

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Study of the Operability of Nonideal Continuous Bioreactors

Cited by 4 publications

References 46 publications

Mathematical modelling of ideal and non‐ideal continuous stirred tank bioreactor using simulated solution

Mathematical modelling of ideal and non‐ideal continuous stirred tank bioreactor using simulated solution

Steady-state analysis of activated sludge processes with a settler model including sludge compression

Analysis of a Chemostat Model with Variable Yield Coefficient and Substrate Inhibition: Contois Growth Kinetics

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