Study of the relationship between cigarette smoking, alcohol drinking and cognitive impairment among elderly people in China

Zhou, Huadong; Deng, Juan; Li, Jingcheng; Wang, Yanjiang; Zhang, Meng; He, Hongbo

doi:10.1093/ageing/32.2.205

Cited by 101 publications

(92 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our previous community-based epidemiological study, the prevalence of cognitive impairment was estimated as 11% in elderly people of the same area as in this study [16] . Compared with the previous study, the frequency of being cognitively impaired 3 months after ischemic stroke was increased by a factor of 3 in the present study.…”

Section: Discussionmentioning

confidence: 58%

“…Language function was tested using the MMSE language items and RVR [15] . The norms for these tests had previously been established in a community group of elderly living in the same urban area with the same age, sex distribution, and educational level [16] . The boundary scores of the MMSE were defi ned as 17 (illiteracy), 20 ( ^ 6 years of education), and 24 ( 1 6 years of education).…”

Section: Evaluation Of Poststroke Cognitive Statusmentioning

confidence: 99%

See 1 more Smart Citation

Frequency and Risk Factors of Vascular Cognitive Impairment Three Months after Ischemic Stroke in China: The Chongqing Stroke Study

Zhou

Wang

et al. 2004

Neuroepidemiology

View full text Add to dashboard Cite

Background: Frequency of poststroke cognitive impairment is high in western countries, and the risk factors of poststroke cognitive impairment have not been fully understood yet. We sought to examine the frequency and risk factors of cognitive impairment after ischemic stroke in a large stroke cohort of China. Methods: A total of 434 consecutive patients with ischemic stroke were enrolled. The cognitive status before and 3 months after stroke was evaluated using the Informant Questionnaire on Cognitive Decline in the Elderly and the Mini-Mental State Examination, respectively. Poststroke cognitive impairment was defined as cognitive impairment with concomitant stroke, stroke-related cognitive impairment was defined as cognitive impairment developing after index stroke, and cognitive impairment after first-ever stroke was defined as cognitive impairment developing after first-ever stroke. Logistic regression analysis was used to find the risk factors of cognitive impairment after stroke. Results: (1) Frequency of poststroke cognitive impairment was 37.1%, that of stroke-related cognitive impairment was 32.2%, and that of cognitive impairment after first-ever stroke was 29.6%. (2) The patients with cognitive impairment more often had older age, low educational level, atrial fibrillation, prior stroke, everyday drinking, left carotid territory infarction, multiple lesions, embolism, and dysphasia. (3) The factors associated with poststroke cognitive impairment in logistic regression analysis were age (OR 1.215, 95% CI 1.163–1.268), low educational level (OR 2.023, 95% CI 1.171–3.494), prior stroke (OR 5.130, 95% CI 2.875–9.157), everyday drinking (OR 2.013, 95% CI 1.123–3.607), dysphasia (OR 3.994, 95% CI 1.749–9.120), and left carotid territory infarction (OR 2.685, 95% CI 1.595–4.521). Conclusions: Cognitive impairment is common 3 months after ischemic stroke in Chinese people. Risk factors for poststroke cognitive impairment include age, low educational level, everyday drinking, prior stroke, dysphasia, and left carotid territory infarction.

show abstract

Section: Discussionmentioning

confidence: 58%

Section: Evaluation Of Poststroke Cognitive Statusmentioning

confidence: 99%

Frequency and Risk Factors of Vascular Cognitive Impairment Three Months after Ischemic Stroke in China: The Chongqing Stroke Study

Zhou

Wang

et al. 2004

Neuroepidemiology

View full text Add to dashboard Cite

show abstract

“…We selected as potential time-varying confounding variables: age, equivalized income (27), medical treatment for stroke, hypertension, diabetes (28), dyslipidemia (29), current smoking (30), current alcohol drinking (31), and daily walking time (32). Other time invariant characteristics, such as sex and educational attainment, were omitted from our fixed-effects regressions (33).…”

Section: Methodsmentioning

confidence: 99%

Increased risk of dementia in the aftermath of the 2011 Great East Japan Earthquake and Tsunami

Hikichi

Aida

Kondo

et al. 2016

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

No previous study has been able to examine the association by taking account of risk factors for dementia before and after the disaster. We prospectively examined whether experiences of a disaster were associated with cognitive decline in the aftermath of the 2011 Great East Japan Earthquake and Tsunami. The baseline for our natural experiment was established in a survey of older community-dwelling adults who lived 80 km west of the epicenter 7 mo before the earthquake and tsunami. Approximately 2.5 y after the disaster, the follow-up survey gathered information about personal experiences of disaster as well as incidence of dementia from 3,594 survivors (82.1% follow-up rate). Our primary outcome was dementia diagnosis ascertained by in-home assessment during the follow-up period. Among our analytic sample (n = 3,566), 38.0% reported losing relatives or friends in the disaster, and 58.9% reported property damage. Fixed-effects regression indicated that major housing damage and home destroyed were associated with cognitive decline: regression coefficient for levels of dementia symptoms = 0.12, 95% confidence interval (CI): 0.01 to 0.23 and coefficient = 0.29, 95% CI: 0.17 to 0.40, respectively. The effect size of destroyed home is comparable to the impact of incident stroke (coefficient = 0.24, 95% CI: 0.11 to 0.36). The association between housing damage and cognitive decline remained statistically significant in the instrumental variable analysis. Housing damage appears to be an important risk factor for cognitive decline among older survivors in natural disasters.instrumental variable analysis U p to two-thirds of the affected populations in the 2011 Great East Japan Earthquake and Tsunami were older residents who were 60 y old or older (1). Recovery after major disaster poses a unique set of challenges for the elderly population, including disruption of medical care for preexisting conditions, preexisting functional limitations that impede recovery, and social isolation in the aftermath of housing loss and resettlement. A particular concern for older survivors is the potential risks of cognitive decline. In the 2011 earthquake and tsunami, an estimated 340,000 residents were displaced as a result of widespread destruction to residential properties. In turn, as a direct consequence of residential dislocation and resettlement in unfamiliar surroundings, many seniors experienced disorientation that could hasten cognitive decline (2). Psychological trauma, including posttraumatic stress disorder (PTSD) symptoms (3) and the onset of depression (4), may have additionally contributed to this risk.Two years after the 2011 Great East Japan Earthquake and Tsunami, a cross-sectional study found that 36.0% of seniors who moved to temporary housing in Kesen-numa city were suffering from dementia symptoms (5). Another cross-sectional study of seniors affected by the disaster reported that 47.9% showed signs of mild cognitive impairment, and an additional 16.0% of respondents were diagnosed as having dementia (6). However, ...

show abstract

“…Levels of sICAM-1, sVCAM-1 and sE-selectin of serum samples from 30 age- and gender-matched healthy people were measured and used as normal control [12]. …”

Section: Methodsmentioning

confidence: 99%

Association of Soluble Intercellular Adhesion Molecule 1 with Neurological Deterioration of Ischemic Stroke: The Chongqing Stroke Study

Wang

Zhou

et al. 2006

Cerebrovasc Dis

View full text Add to dashboard Cite

Background: Adhesion molecules play important roles in the pathophysiology of ischemic stroke. The aim of the present study was to investigate whether serum levels of soluble intercellular adhesion molecule 1 (sICAM-1), soluble vascular cellular adhesion molecule 1 (sVCAM-1) and soluble E-selectin were associated with neurological deterioration of ischemic stroke. Methods: 238 consecutive patients with ischemic stroke examined within 24 h from onset were enrolled into the study. The stroke severity was daily assessed with the NIH Stroke Scale (NIHSS) within the first week after admission. Serum levels of sICAM-1, sVCAM-1 and sE-selectin after admission were measured using enzyme-linked immunosorbent assay. Multivariate logistic regression was used to analyze the association of serum levels of sICAM-1, sVCAM-1 and sE-selectin on admission with the neurological deterioration of ischemic stroke, adjusted for potential confounders. Results: 52 (21.8%) out of 238 stroke patients suffered from neurological deterioration. Serum levels of sICAM-1 on admission of stroke patients were significantly higher than those of healthy controls. Compared with patients without deterioration, patients with neurological deterioration had higher levels of sICAM-1, but not of sVCAM-1 and sE-selectin. On multivariate logistic regression, the serum level of sICAM-1 on admission was associated with neurological deterioration of stroke (OR 2.92, 95% CI 1.41–6.05). Other variables associated with neurological deterioration were fasting serum glucose (OR 1.65, 95% CI 1.24–2.20), baseline fibrinogen (OR 1.31, 95% CI 1.13–1.52) and NIHSS score (OR 1.23, 95% CI 1.15–1.32). Conclusions: The serum level of sICAM-1 on admission is associated with neurological deterioration of ischemic stroke.

show abstract

Study of the relationship between cigarette smoking, alcohol drinking and cognitive impairment among elderly people in China

Abstract: smoking and drinking are risk factors for cognitive impairment among elderly people. Cessation of smoking and reduction of drinking could be considered as part of a strategy to reduce the incidence of cognitive impairment.

Cited by 101 publications

References 21 publications

Frequency and Risk Factors of Vascular Cognitive Impairment Three Months after Ischemic Stroke in China: The Chongqing Stroke Study

Frequency and Risk Factors of Vascular Cognitive Impairment Three Months after Ischemic Stroke in China: The Chongqing Stroke Study

Increased risk of dementia in the aftermath of the 2011 Great East Japan Earthquake and Tsunami

Association of Soluble Intercellular Adhesion Molecule 1 with Neurological Deterioration of Ischemic Stroke: The Chongqing Stroke Study

Contact Info

Product

Resources

About