Study of the Role of Per-Operative Peritoneal Lavage With Super Oxidized Solution in Perforation Peritonitis

Abstract

BACKGROUNDThe fundamental in treatment of perforation peritonitis include resuscitation, treatment of septicemia, control of contaminating source and peritoneal toilet. Numerous studies have shown the role of different solutions such as normal saline, antibiotics and betadine as peritoneal lavage in reducing morbidity and mortality of perforation peritonitis. The objective of this study was to present our finding on the role of per-operative peritoneal lavage with super-oxidized solution in cases of perforation peritonitis and its effects on postoperative course and outcome compare to per operative lavage with saline. MATERIALS AND METHODSThe patients were randomized into two groups. In the control group after the definitive surgery for perforation peritonitis, the peritoneal cavity was lavaged with normal saline and closed after putting drain. In study group after definitive surgery the peritoneal cavity was lavaged with saline followed by 100ml of super-oxidized solution and drain were closed for 1h after abdominal closure. The patients were followed up for morbidity and mortality. RESULTIn present study, there was no statistically significance between super-oxidized solution and normal saline lavage group. When we compared it on the basis of postoperative wound infection, fever, burst abdomen and other complication, duration of hospital stay and morbidity and mortality. CONCLUSIONBy this study we concluded that peritoneal lavage by super-oxidized solution or normal saline alone did not make any difference on patient outcome. KEYWORDSSuper-oxidized solution 1; normal saline 2; perforation peritonitis 3. HOW TO CITE THIS ARTICLE:

Intra-operative peritoneal lavage: normal saline, super-oxidized solution, antibiotics, or chemotherapy dilemma

“…Moreover, peritoneal lavage with super-oxidized solution has shown decreased surgical site infection and mortality incidence in emergency laparotomies 8 . However, one study showed that there was no clinical outcome difference between using super-oxidized solution or normal saline alone as a peritoneal lavage fluid 11 .…”