“Study of Treadmill test in Detecting Asymptomatic Coronary Artery Disease in Type 2 Diabetes Mellitus”

Swaminathan, Dr.K.; Gayathri, D.

doi:10.9790/0853-1508080106

Cited by 6 publications

(13 citation statements)

References 6 publications

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“…Similar results were documented by Swaminathan et al in their study. 5 This was also in line with the study done by DeLuca et al which found that dyslipidemia was common among the individuals with type 2 diabetes and the most common abnormality was elevated serum triglyceride levels (73.3%). 6 Yet another Indian study by Gautam et al also proved the above fact by showing had strong correlation of TMT positive diabetics with elevated levels of triglycerides (0.82) and low HDL (-0.81).…”

Section: Discussionsupporting

confidence: 89%

“…In the earlier study, the average HbA1C (%) in Treadmill test positive and negative cases were 9.7and7.7 respectively. 5 Another similar study there was an increasing trend of HbA1c levels with the augmenting number of coronary vessels involvement with CAD (p<0.001). 8 There are several studies which put forth magnetic resonance imaging as the ideal modality for screening myocardial tissue for hidden ischemia.…”

Section: Discussionmentioning

confidence: 63%

“…The results were similar to the prevalence recorded by Swaminathan and Gayathri in their study which showed Treadmill test was positive in 30% (n=15) of the type 2 diabetic cases. 5 The study also showed increased prevalence of silent MI as the duration of diabetes increased. Tread mill test was positive in 4/26 (27%), 3/9 (20%), 5/7 (33%) and 3/5(20%) patient with duration of diabetes ≤5, 6 to 10, 1 to 15, and 16-20 years respectively.…”

Section: Discussionmentioning

confidence: 78%

“…Tread mill test was positive in 4/26 (27%), 3/9 (20%), 5/7 (33%) and 3/5(20%) patient with duration of diabetes ≤5, 6 to 10, 1 to 15, and 16-20 years respectively. 5 There was a significant difference (p<0.001) of mean duration of diabetes among those with TMT documented silent MI (8.2±2.6 years) than those without silent MI (5.2±1.1 years) ( Table 2). In the present study authors found that the serum triglyceride levels, LDL and cholesterol levels were significantly higher in the TMT positive group compared to the TMT negative group.…”

Section: Discussionmentioning

confidence: 90%

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Prevalence and clinical predictors of silent myocardial ischemia in asymptomatic type 2 Diabetes Mellitus patients at Puducherry, India

Hussain

2018

Int J Adv Med

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Background: Silent MI is common among diabetics due to autonomic dysfunction and loss of pain alert mechanism. There are various risk factors associated with silent MI in diabetes which needs screening earlier to prevent unanticipated cardiovascular mortality. The objective of the present investigation was to study the prevalence and clinical factors associated with silent myocardial ischemia as diagnosed by TMT among type 2 diabetics who had no previous history or symptoms of cardio-vascular disease.Methods: A total of 200 type 2 diabetes affected subjects with duration of diabetes for at least 6 months, above 18 years of age, attending to the diabetology OPD, during the time period June 2017 to May 2018 were included in the study. Blood investigations and TMT were done for all the participants and documented in a proforma.Results: Silent MI was documented by using TMT in 36.5% (n=73) of patients with type 2 diabetes mellitus. The factors like age (59.1±16.3 years), duration of diabetes (8.2±2.6 years), obesity (BMI=29.6±4.7 kg/m2), Glycated haemoglobin (9.7±2.8 %), lipid levels and post-prandial blood sugar levels (236±11.8 mg/dl) associated well with silent MI as predicted by TMT. Fasting blood sugar did not show significant association with Silent MI.Conclusions: The prevalence of silent MI was higher among the type 2 diabetic individuals compared to non-diabetics. Age, duration of diabetes, HbA1c levels, BMI, dyslipidemia and post prandial blood glucose levels were associated significantly with incidence of silent MI in patients with type 2 diabetes.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 90%

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Prevalence and clinical predictors of silent myocardial ischemia in asymptomatic type 2 Diabetes Mellitus patients at Puducherry, India

Hussain

2018

Int J Adv Med

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“…The mean age study subjects were 54.7 years. Similar results were seen by Swaminathan K et al 13 (52.3 ± 5.6) and Lavekar AS et al 14 (53.56 ± 7.41). This may reflect the health-seeking behaviour of study subjects after the age of 40 years.…”

Section: Discussionsupporting

confidence: 88%

Evaluation of Silent Myocardial Ischemia in Asymptomatic Type 2 Diabetes Mellitus Patients by Tread Mill Test in Tertiary Care Center in South India

Reddy¹,

Anandkumar²,

Rao³

2019

jemds

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BACKGROUND Diabetes is an important and treatable risk factor for Coronary Artery Disease (CAD). Routine electrocardiography (ECG) and cardiac imaging cannot diagnose these patients. Hence the present study was done to estimate the prevalence of silent myocardial ischemia (SMI) in asymptomatic type 2 diabetic patients by Tread Mill Test (TMT). Assess the role of Tread Mill Test (TMT) in detecting the prevalence of silent myocardial ischemia (SMI) in type 2 diabetic patients. MATERIALS AND METHODS Asymptomatic diabetes mellitus (DM) patients aged 30 to 60 years with a normal resting ECG and echocardiography (ECHO) were included in the study. A detailed clinical history, a thorough medical examination and relevant biochemical parameters were analysed in all study subjects. The treadmill test was performed on each participant according to the Bruce protocol. RESULTS In this study, the prevalence of silent myocardial ischaemia in asymptomatic DM patients was 22.2%, as shown by positive TMT test. Among these study subjects, 10 (22.7%) were males and 6 (21.4%) were females. Among the risk factors, association of age, duration of diabetes, HbA1c levels were correlated with TMT positivity for inducible ischemia. CONCLUSION The silent nature of CAD in many diabetes patients makes remain undiagnosed for long periods of time. Hence there is a need for screening of diabetes patients for MI. In a rural setup where there are limited resources, TMT can be used as a screening tool for diagnosing SMI. Elderly diabetics with longer duration of diabetes and poor glycemic control had higher prevalence of inducible ischemia. Good glycemic control had a protective effect against development CAD.

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Role of Treadmill testing (TMT) in Type Two diabetic Patients in Kirkuk - A Prospective Clinical Study

Salih¹,

Mohammed²

2018

Int.J.Curr.Res.Aca.Rev.

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Article Info Coronary artery disease is the common impact of death worldwide in type 2 Diabetes mellitus. High rate of asymptomatic coronary heart disease in type 2 DM. Stress testing, and subsequent intervention, might reduce patients" risk of cardiovascular morbidity and mortality. Hence a prospective study conducted during the period 2016-2017We studied the prevalence of silent myocardial ischemia (SMI) in asymptomatic type 2 diabetes mellitus by using treadmill test. Further analysis was performed using binary logistic regression for the predictors of positive TMT findings in DM patients in this study, the duration of DM was the stronger significant predictor of positive TMT, [odds ratio (OR = 2.79), P = 0.002], patients with longer duration of DM were about 2.8-fold more likely to have positive TMT findings. Being old age diabetic male patient increase the risk of having positive TMT by almost 1.82 folds (OR = 1.82, P = 0.023), other were higher level of Triglycerides (OR = 1.68), larger BMI (OR = 1.44), and male gender (OR = 1.33). In conclusion, the current study documented that a significant proportion of type two diabetes mellitus patients had silent myocardial Ischemia detected by treadmill testing which showed an important role in detecting the silent myocardial ischemia older age, male gender, longer duration of diabetes, large body mass index and elevated triglycerides levels are significant predictors of silent myocardial ischemia in diabetic patients.

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“Study of Treadmill test in Detecting Asymptomatic Coronary Artery Disease in Type 2 Diabetes Mellitus”

Cited by 6 publications

References 6 publications

Prevalence and clinical predictors of silent myocardial ischemia in asymptomatic type 2 Diabetes Mellitus patients at Puducherry, India

Prevalence and clinical predictors of silent myocardial ischemia in asymptomatic type 2 Diabetes Mellitus patients at Puducherry, India

Evaluation of Silent Myocardial Ischemia in Asymptomatic Type 2 Diabetes Mellitus Patients by Tread Mill Test in Tertiary Care Center in South India

Role of Treadmill testing (TMT) in Type Two diabetic Patients in Kirkuk - A Prospective Clinical Study

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