Vanadium-titanium magnetite has coarse particle size, small specific surface area, poor surface hydrophilicity and low strength when being made into pellets. However, vanadium-titanium magnetite pellet also has a certain application requirement due to its large reserves and high comprehensive utilisation value. Therefore, this article investigated the effects of water ratio, bentonite ratio, vanadium-titanium magnetite ratio, CaO ratio and roasting temperature on the strength of pellets. The results showed that better parameters of green pellets were obtained as follows: the water ratio was 9%, the bentonite ratio was 2.5% and the vanadium-titanium magnetite ratio was 25%. There was no obvious relationship between the CaO ratio and green pellet strength. Better preparation parameters of roasted pellets were as follows: water ratio was 9%, bentonite ratio 2%, vanadium-titanium magnetite ratio 25%, CaO ratio 1% and roasting temperature 1300°C. This provides guidance for the effective use of vanadium-titanium magnetite.