Study of various factors affecting compliance in schizophrenia: A single center experience in India

Abstract

Aim of the study: Schizophrenia is a major psychiatric disorder, imparting a major burden in health care sector. Many treatments are available now a days to treat schizophrenia, although, its burden is not decreasing. The main reason behind this is noncompliance to treatment. This study aims to find out the noncompliance prevalence and to study influence of sociodemographic factors, treatment related variables, illness related variables and various subjective reasoning in patients with schizophrenia.Material and methods: Over the period of 1 year, 80 patients with schizophrenia who gave written informed consent were enrolled in the study and their sociodemographic, treatment related and illness related variables were noted. PANSS(positive and negative syndrome scale for Schizophrenia) was used to indicate the severity of illness. ROMI(Rating of Medication Influences Scale in Schizophrenia) was used to assess subjective reasons. Chi square test was used to find out statistical significance.Results: 37.5% patients were non-compliant in our study. Education, the illness severity, the type of regimen and dosages of medication have a significant influence on treatment compliance. The subjective reason "no perceived benefit" is significantly associated with treatment noncompliance.

Medication nonadherence and its associated factors in psychiatric patients in India: A systematic review and meta-analysis

“…Most studies did not find any association between age and MNA. [ 7 , 10 , 14 , 20 , 33 , 36 , 37 , 39 - 41 , 47 , 49 ] Younger-age group had better adherence in one study,[ 21 ] while a lower age was associated with poorer adherence in two studies. [ 24 , 35 ] Several studies did not find any association between gender and MNA.…”

“…[ 24 , 35 ] Several studies did not find any association between gender and MNA. [ 10 , 15 , 17 , 20 , 21 , 24 , 36 - 38 , 40 , 41 , 46 , 47 ] Four studies found that compliance was better in females,[ 25 , 26 , 33 , 35 ] while one study found that female gender was associated with MNA. [ 7 ] Most studies did not find any association between education and MNA.…”

“…[ 7 , 10 , 15 , 17 , 21 , 24 , 33 , 35 , 37 , 39 , 40 , 46 ] Lower education was associated with noncompliance in some studies[ 20 , 26 ] and greater literacy was associated with better compliance in one study. [ 41 ] Marital status did not associate with MNA. [ 7 , 10 , 17 , 20 , 21 , 24 , 26 , 33 , 35 - 37 , 41 , 49 ]…”

Adherence to Clinic Appointments and Medication Among Patients Accessing Mental Health Clinics in Lilongwe, Malawi

“…The World Health Organization (WHO) describes medication nonadherence as "a case in which a person's behavior in taking medication does not correspond with agreed recommendations from health personnel" (Semahegn et al, 2020). In contrast, nonadherence was de ned as a failure to follow instructions and advice from service providers (Shah et al, 2019). Nonadherent patients are reported to be 70% more likely to be admitted to the hospital (Ljungdalh, 2017).…”

Clinic appointments and medication adherence among patients accessing mental health services in Central Malawi: A cross-sectional analytical study

“…The World Health Organization (WHO) describes medication non-adherence as "a case in which a person's behaviour in taking medication does not correspond with agreed recommendations from health personnel (Semahegn et al, 2020). Contrastingly, non-adherence has been de ned as a failure to follow instructions and advice from service providers (Shah et al, 2019). Non-adherent patients are reported to be 70% more likely to be admitted to the hospital (Ljungdalh, 2017).. Non-adherence in mental diseases ranges from 70% to 80%, and in depression alone and bipolar disorder, it is between 26.5% and 70% (Alpak et al, 2015).…”