Study of Various Organisms Associated with Surgical Site Infection and their Sensitivity Pattern

Abstract

Aim: The objectives of this study was to study the various microorganisms causing surgical site infection, to study their antibiotic sensitivity and resistance pattern. Setting: Department of Surgery of a tertiary health care centre with an attached medical college. Material and methods: A total of 89 patients with post operative surgical site infection occurring within 30 days of surgery or 1 year of implant were included as subject material after they satisfy inclusion and exclusion criteria. Results: E.coli is the commonest organism isolated in SSI wounds. Overall Imipenem and Amikacin are the most sensitive antibiotics. Over all gentamycin, cefotaxime and clindamycin are the most resistant antibiotics noted. Conclusion: The most common organisms associated with SSI are E. coli and Pseudomonas. Most of the organisms were sensitive to imipenem, amikacin. Sensitivity pattern of the of the organism is changing with time. The common organisms are now no longer sensitive to routinely used cheaper antibiotics. Newer antibiotics, which are more costly, are required to treat the infection which is a burden to the patient.

High Prevalence of Antibiotic-Resistant Gram-Negative Bacteria Causing Surgical Site Infection in a Tertiary Care Hospital of Northeast India

“…But some studies corroborate our findings. Borse et al, Dessie et al, and Amare et al found E. coli to be the commonest organism (32.58%, 23.1%, and 24.3%, respectively) causing SSI [ 16 - 18 ]. The predominance of GNBs in our study which covered almost two-thirds of the total isolates points towards a difference in organism profile in LMIC compared to high-income countries, especially in resource-scant healthcare facilities.…”

A Study of Surgical Site Infections in Abdominal Surgeries

“…The most common organisms associated are Gram positive organisms like, Staphylococcus and Streptococcus, followed by E.coli, Klebsiella and Pseudomonas. 3 Risk factors responsible for causing SSIs are -age of patient, underlying pre-existing illness stratified based on American Society of Anesthesiologists (ASA) Preoperative Risk Classification, obesity, smoking, other patient factors like trauma, blood transfusions, hypothermia, shock, etc., adequate pre-operative preparation of patient, pre-operative antibiotic prophylaxis, 4,5 intra-operative precautions, and post-operative management.…”