Study of Various Organisms Associated with Surgical Site Infection and their Sensitivity Pattern

Borse, Hemant; Shelke, Rahul D.

doi:10.18311/mvpjms/2015/v2/i2/785

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…We found a dominance of Gram-positive pathogens compared to the literature, which showed to be an independent risk factor in the multivariate analysis. In the literature, Gram-negative bacteria such as Klebsiella species or Escheria coli are described as frequent pathogens of a SSI [ 26 – 28 ]. The difference to our study may be due to the fact that most patients in our study received antibiotic therapy that adequately covered these pathogens.…”

Section: Discussionmentioning

confidence: 99%

Abdominal fascia dehiscence: is there a connection to a special microbial spectrum?

Stropnicky

Kandemir

Schäffer

et al. 2022

Hernia

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Introduction Acute fascia dehiscence (FD) is a threatening complication occurring in 0.4–3.5% of cases after abdominal surgery. Prolonged hospital stay, increased mortality and increased rate of incisional hernias could be following consequences. Several risk factors are controversially discussed. Even though surgical infection is a known, indisputable risk factor, it is still not proven if a special spectrum of pathogens is responsible. In this study, we investigated if a specific spectrum of microbial pathogens is associated with FD. Methods We performed a retrospective matched pair analysis of 53 consecutive patients with an FD after abdominal surgery in 2010–2016. Matching criteria were gender, age, primary procedure and surgeon. The primary endpoint was the frequency of pathogens detected intraoperatively, the secondary endpoint was the occurrence of risk factors in patients with (FD) and without (nFD) FD. Results Intraabdominal pathogens were detected more often in the FD group (p = 0.039), with a higher number of Gram-positive pathogens. Enterococci were the most common pathogen (p = 0.002), not covered in 73% (FD group) compared to 22% (nFD group) by the given antibiotic therapy. Multivariable analysis showed detection of Gram-positive pathogens, detection of enterococci in primary laparotomy beside chronic lung disease, surgical site infections and continuous steroid therapy as independent risk factors. Conclusion Risk factors are factors that reduce wound healing or increase intra-abdominal pressure. Furthermore detection of Gram-positive pathogens especially enterococci was detected as an independent risk factor and its empirical coverage could be advantageous for high-risk patients.

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Section: Discussionmentioning

confidence: 99%

Abdominal fascia dehiscence: is there a connection to a special microbial spectrum?

Stropnicky

Kandemir

Schäffer

et al. 2022

Hernia

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Study of Single Dose of Antibiotic Prophylaxis in Clean Surgeries at a Tertiary Care Centre

Hemantkumar

Ameya

2022

MVP.J.M.S

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Background: Pre-operative single dose antibiotic prophylaxis has shown to reduce the incidence of surgical site infections and thereby patient morbidity. Aims: To evaluate effectiveness of single dose antibiotic prophylaxis in clean surgeries at a tertiary care hospital. Material and Methods: A total of 72 patients undergoing clean surgeries were included after they satisfied the inclusion and exclusion criteria. Results: Single dose of an intravenous prophylaxis of ceftriaxone in clean surgeries excisional biopsy of lipoma, dermoid cyst, sebaceous cyst, enucleation of fibroadenoma, herniotomy, eversion of hydrocele etc. was efficacious in preventing surgical site infection. Surgical site infection was associated with patient’s age, lower haemoglobin levels and longer hospital stay in 3 out of 72 patients. Conclusion: In the present study it was observed that prophylactic single shot of antibiotic is efficacious in averting surgical site infection and is economical for patients undergoing clean surgeries. Factors associated with surgical site infection were patient’s age, haemoglobin and associated co-morbidity like diabetes.

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A Study of Surgical Site Infections in Abdominal Surgeries

Rao¹,

Rao²,

Kumar³

et al. 2019

jebmh

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BACKGROUNDInfections that occur in the wound created by an invasive surgical procedure are generally referred to as surgical site infections (SSIs). Abdominal surgical site infections are among the most common infectious complications in hospitalized patients and are associated with serious consequences for outcomes and costs. They account for up to 14% of SSIs in studies conducted in developing countries. The present study aims to determine the frequency of surgical site infections in patients undergoing various abdominal surgical procedures and the associated risk factors, the organisms implicated and their sensitivity patterns, and the outcomes observed after treatment. METHODSDetails of the patients who developed SSI following abdominal surgeries were recorded in a proforma which included relevant information with regard to history, clinical examination and perioperative management. A cross-sectional study was performed on 100 patients who developed SSI following abdominal surgeries. The type of SSI, the risk factors encountered, the causative organisms isolated and their sensitivity patterns and the outcomes following treatment were studied. RESULTS100 out of 867 patients who underwent abdominal surgeries, both elective and emergency, over a period of 24 months, developed SSI at the rate of 11.53% (7.05% elective and 19.42% emergency). Surgery for duodenal ulcer perforation was the most common abdominal procedure to develop SSI. Smoking, anaemia and blood transfusions were the most frequent risk factors. Majority of the cultures yielded E.coli, Klebsiella and Staphylococcus aureus species. Most were superficial incisional SSIs and resolved after drainage of pus, mostly by the removal of a stitch.

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Study of Various Organisms Associated with Surgical Site Infection and their Sensitivity Pattern

Cited by 4 publications

References 2 publications

Abdominal fascia dehiscence: is there a connection to a special microbial spectrum?

Abdominal fascia dehiscence: is there a connection to a special microbial spectrum?

Study of Single Dose of Antibiotic Prophylaxis in Clean Surgeries at a Tertiary Care Centre

A Study of Surgical Site Infections in Abdominal Surgeries

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