Study on correlation of obesity with short-term prognosis in acute myocardial infarction

Vellani, Haridasan; Rajesh, K.F.; Sajeev, C.G.; Rajesh, Gopalan Nair; Bastion, Cicy; Vinayakumar, Desabandhu; Kadermuneer, P.; Mathew, Dolly; George, Biju; Krishnan, M.N.

doi:10.1016/j.ihj.2015.09.019

Cited by 6 publications

(5 citation statements)

References 24 publications

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“…In the current study, BMI was not recognized as an independent predictor for in-hospital death. This agreed with multiple studies that acknowledged that obese patients had significantly lower in-hospital and overall mortalities [ 22 - 23 ]. Obesity was not an independent predictor of overall mortality after multivariate analysis.…”

Section: Discussionsupporting

confidence: 91%

“…Although LVEF tended to be higher in obese patients, similar results to Harrison et al [ 22 ], RV systolic function was more affected among them. This can be due to obesity-related pulmonary diseases, which may cause more burden on right ventricular performance, including obstructive sleep apnea, episodes of subclinical hypoxemia, high risk of recurrent DVT, and pulmonary embolization.…”

Section: Discussionsupporting

confidence: 86%

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Obesity Influences on Patients With Non-valvular Cardiomyopathy in Relation to Early In-Hospital Outcomes and Health System Burden

Shalaby¹,

Samarin²,

Alabbasi³

et al. 2022

Cureus

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Background Our study aimed to assess the burden of obesity on the health system and outcomes in patients with non-valvular cardiomyopathy. Methods A retrospective analytical cohort, single-center study was conducted at King Abdullah Medical City (KAMC), Makkah, from June 2019 to June 2020, and includes all non-valvular cardiomyopathy (NVCM) patients. The patients were divided into two groups, obese (BMI ≥ 30) and non-obese (BMI<30). The two groups were compared using a t-test and a chi-squared test for continuous and categorical data and regression analysis. Results A single-center, retrospective study was conducted at KAMC, Makkah, and included all NVCM patients (ejection fraction or EF ≤ 45%) who were admitted during this study period. A total of 626 NVCM patients were included in this cohort study; they had a mean BMI of 29 ± 8.1 and a mean EF of 28.4 ± 9.7. Patients were divided into two groups, obese (BMI ≥ 30) and non-obese (BMI<30). Obese patients represented 37% (n=231) of our study population. The non-ischemic category of cardiomyopathy had a higher prevalence among the obese (35% vs 27%). A higher percentage of obese patients presented with heart failure (HF) symptoms rather than ischemia or arrhythmia (46%, 40%, and 7% for HF symptoms, ischemia, and arrhythmia, respectively). There was no significant difference in NVCM complications, including cardiogenic shock, pulmonary edema, and cardiac arrest, between the two groups. Obese patients had a significantly higher post-myocardial infarction (MI) ejection fraction (29.7±9.7 vs 27.5±9.7, p=0.01). We found a statistically significant positive correlation between BMI and length of in-hospital stay (P=0.04). In-hospital mortality was non-significantly different between our two groups, although numerically, it was higher among the non-obese group (obesity paradox) (10% vs 12%, p=0.2). Type of cardiomyopathy, cerebrovascular stroke, smoking, and sacubitril/valsartan intake were detected as independent predictors of in-hospital mortality among our patients. Conclusions Obesity among NVCM patients sets more burden on health facilities by the prolongation of the in-hospital stay of patients although BMI is not an independent predictor of death in those patients.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 86%

Obesity Influences on Patients With Non-valvular Cardiomyopathy in Relation to Early In-Hospital Outcomes and Health System Burden

Shalaby¹,

Samarin²,

Alabbasi³

et al. 2022

Cureus

View full text Add to dashboard Cite

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“…A previous study revealed that the incidence of CVD in an obese population was significantly higher than that in a normal population, and obesity was a risk factor for cardiovascular events, which increased the risk of death induced by CVD (19). Another study revealed that in patients with chronic diseases, the prognosis of patients with obesity and overweight may be better, compared to patients with normal BMI.…”

Section: Discussionmentioning

confidence: 99%

Correlation of triglycerides with myocardial infarction and analysis of risk factors for myocardial infarction in patients with elevated triglyceride

Jiao¹,

Li²,

Li³

et al. 2018

J. Thorac. Dis.

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“…With regards to ventricular systolic function post AMI, in our study LVEF was found to be less affected in overweight and obese population. Similarly, Haridasan et al [14] stated that obese and overweight groups were significantly younger, with better LVEF and they were mostly males with an elevated HTN, DM, and hyperlipidemia prevalence.…”

Section: Discussionmentioning

confidence: 91%

Obesity Impacts on Acute Myocardial Infarction Patients Relevant to Hospital Management and Outcomes – Single Center Experience

Ibrahim¹,

Khaled²,

Shalaby³

2023

The Egyptian Journal of Hospital Medicine

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Background: Obesity is considered a hazard factor for ischemic heart disease (IHD). However, it has been proposed that obese people may have a good prognosis after cardiac events, a phenomenon identified as the "obesity paradox". Objective: The aim of the present study was to examine the effect of body mass index (BMI) on clinical manifestations and outcomes following acute myocardial infarction (AMI). Patients and methods: A retrospective, single center research was conducted at KAMC, Makkah during 2015-2020. AMI cases were allocated into three groups; Group 1 included non-obese (BMI<25) patients, Group 2 included overweight (25≥BMI<30) and Group 3 included obese (BMI≥30). Results: A total of 3018 AMI cases were enrolled in our study, of whom 834 (28%) patients were obese. Obese cases came with AMI at a younger age than overweight and non-obese ones respectively (P<0.001). Overweight and obese groups were more diabetics, hypertensive, and dyslipidemic. Contrast volume used during coronary angiography (CAG) was much elevated in obese patients than other groups (P<0.001). Overweight and obese patient groups were more in need for thrombus aspiration during CAG than non-obese (40, 38 %, and 22% respectively, P<0.001), and tirofiban use post-procedure (46%, 31%, and 24% respectively, P=0.008) in comparison to the non-obese patient group. Obese patients were less common to have multivessel disease compared to overweight and non-obese groups (24%, 43%, and 33%, respectively, P=0.01). Post-MI ejection fraction has a tendency to be much higher in obese and overweight patients in comparison to non-obese group. Conclusion: Obese patients presented with AMI at a younger age and consequently less common to have multivessel disease.

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Study on correlation of obesity with short-term prognosis in acute myocardial infarction

Abstract: Low BMI and normal WC were associated with a worse short-term outcome in patients with acute MI. Neither BMI nor WC independently predicted cardiac events or death after acute MI.

Cited by 6 publications

References 24 publications

Obesity Influences on Patients With Non-valvular Cardiomyopathy in Relation to Early In-Hospital Outcomes and Health System Burden

Obesity Influences on Patients With Non-valvular Cardiomyopathy in Relation to Early In-Hospital Outcomes and Health System Burden

Correlation of triglycerides with myocardial infarction and analysis of risk factors for myocardial infarction in patients with elevated triglyceride

Obesity Impacts on Acute Myocardial Infarction Patients Relevant to Hospital Management and Outcomes – Single Center Experience

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