Study on Difference in Olfactory Response in Dysosmia Patients

Shibuya, Enatsu; Asahina, Norihiko; Suzuki, Emiko; Suzaki, Harumi

doi:10.3950/jibiinkoka.105.783

Cited by 2 publications

(1 citation statement)

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“…The odour detection acuity and odour recognition acuity were evaluated in all subjects by means of the T & T olfaction test (Takasuna Co., Ltd, Tokyo, Japan) prior to the experiments. T & T testing is well correlated with the University of Pennsylvania Smell Identification Test (Kondo et al 1998) and is commonly used in Japan to test acuity of olfactory response for patients with dysosmia (Shibuya et al 2002). The test is used with five odours (odour A, β‐phenyl ethyl alcohol; odour B, methyl cyclopentenolone; odour C, iso‐valeric acid; odour D, γ‐undecalactone; odour E, skatole).…”

Section: Methodsmentioning

confidence: 99%

Inspiratory phase‐locked alpha oscillation in human olfaction: source generators estimated by a dipole tracing method

Masaoka

Koiwa

Homma

2005

The Journal of Physiology

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Olfactory perception and related emotions are largely dependent on inspiration. We acquired simultaneous respiration and electroencephalographic recordings during pleasant odour and unpleasant odour stimulation. We sought to identify changes in respiratory pattern, inspiratory-related potentials and location of dipoles estimated from the potentials. Electroencephalographic recording was triggered by inspiration onset. Respiratory frequency decreased at pleasant odour recognition, and it increased at unpleasant odour detection and recognition. O 2 consumption records showed that these changes were not due to metabolic demand. During olfactory stimulation, inspiratory phase-locked alpha oscillation (I-α) was found in the averaged potential triggered by inspiration onset. I-α was observed at both pleasant odour and unpleasant odour detection and recognition, but it was not seen in the inspiration-triggered potentials of normal air breathing. Electroencephalographic dipole tracing identified the location of dipoles from the I-α in the limbic area and the cortex; the entorhinal cortex, hippocampus, amygdala, premotor area and centroposterior orbitofrontal cortex subserve odour detection, and the rostromedial orbitofrontal cortex subserves odour recognition. We suggest that the I-α in our study originated from the olfactory cortex in the forebrain and was phase-locked to inspiration.

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Section: Methodsmentioning

confidence: 99%