In modern buildings are also currently used the wooden-based construction systems. A wide range of uses the timber constructions in apartment buildings is a vision of the countries of the EU. The use of timber and the other recyclable materials in apartment buildings creates the precondition for the implementation, operation and disposal of environmental impacts of the EU 2020 Strategy. In the long term is important to transform the construction of buildings to a sustainable standard, which the application of wood in construction supports. Currently, the fire height of timber-based residential construction in most EU countries is limited to 5 storeys, provided that the timber structures are fire-protected. This paper deals with the influence of the ventilation parameter in the time and the intensity of the gas temperature during a fire in a model of an apartment building with a timber load-bearing structure. The load-bearing structure is made of CLT panels, with a mixed structural unit, i.e. with fire-resistant cladding of all load-bearing and fire-dividing structures. FDS (Fire Dynamics Simulator - PyroSim software) is used for dynamic simulations of fire in the model apartment.