Abstract-This paper focuses on the evaluation of operational conditions such as temperature, exposure time and flux on the polarization of a Schottky electron collection CdTe detector. A Schottky e − collection CdTe Medipix3RX hybrid pixel detector was developed as a part of the CALIPSO-HIZPAD2 EU project. The 128 x 128 pixel matrix and 0.75 mm thick CdTe sensor bumpbonded to Medipix3RX readout chips enabled the study of the polarization effects. Single and quad module Medipix3RX chips were used which had 128 x 128 and 256 x 256 pixel matrices, respectively. This study reports the sensor-level and pixel-level polarization effects of the detector obtained from a laboratory Xray source. We report that the sensor-level polarization is highly dependent on temperature, flux and exposure time. Furthermore, the study of pixel-level polarization effects led to identification of a new type of pixel behaviour that is characterised by three distinct phases and, thus, named "tri-phase" (3-P) pixels. The 3-P pixels were the dominant cause of degradation of the flat-field image uniformity under high flux operation. A new method of identifying the optimum operational conditions that utilises a criterion related to the 3-P pixels is proposed. A generated optimum operational conditions chart under the new method is reported. The criterion is used for bias voltage reset depolarization of the detector. The method successfully represented the dependency of polarization on temperature, flux and exposure time and was reproducible for multiple sensors. Operating the detector under the 3-P pixel criterion resulted in the total efficiency not falling below 95%.