Study on Phenotypic Detection of Esbl in Gram Negative Bacterial Isolates in a Tertiary Care Hospital in Bangalore

Sangeetha, K.; Hittinahalli, Vivek; Lyra, Patrícia

doi:10.9735/0975-5276.10.3.1049-1051

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…(16,18) Early detection of ESBL and MBL positive isolates is necessary not only for management of the patient but also for appropriate infection control measures to prevent the spread of resistance. (23) In the present study for MBL detection, combined disc diffusion test showed higher positivity (65%) when compared to other two tests and this fact correlates with the findings done by other authors. (24) The double disc synergy test (DDST) less sensitivity because of the problem of optimal disc space.…”

Section: Resultssupporting

confidence: 92%

“…In the present study highest MBL production was seen in Klebsiella pneumoniae 7 (30%) and Pseudomonas spp 5 (22%) which is similar to other studies. (3,16,23) In this study maximum ESBL and MBL production was observed in urine and pus isolates which correlates with other studies. (16,18) Early detection of ESBL and MBL positive isolates is necessary not only for management of the patient but also for appropriate infection control measures to prevent the spread of resistance.…”

Section: Resultssupporting

confidence: 91%

See 1 more Smart Citation

Detection of ESBL and MBL Producing Gram Negative Bacilli from various Clinical Samples at a Tertiary Care Hospital

Iswarya¹,

Shrihari²

2019

Int.J.Curr.Microbiol.App.Sci

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Section: Resultssupporting

confidence: 92%

Section: Resultssupporting

confidence: 91%

Detection of ESBL and MBL Producing Gram Negative Bacilli from various Clinical Samples at a Tertiary Care Hospital

Iswarya¹,

Shrihari²

2019

Int.J.Curr.Microbiol.App.Sci

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“…Our study showed maximum susceptibility to piperacillintazobactam (86%) followed by imipenem (78.4%) and amikacin (63.5%) which is similar to study done by Sangeetha K.T. et al 21 As observed in our study, Imipenem was effective among ESBL producers. Carbapenem should be considered as reserve drug and used only for infections caused for drug resistant organisms.…”

Section: Discussionsupporting

confidence: 91%

ESBL Producers in Gram Negative Isolates from Clinical Samples

Wadekar¹,

Sathish²,

Pooja³

et al. 2020

J Pure Appl Microbiol

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Resistance to beta lactam antibiotics is the most common cause for beta-lactamase production. Increasing number of extended spectrum beta-lactamase (ESBL) producers has reduced the treatment options which resulted in emergence of multidrug resistant strains, treatment failure and hence increased mortality. To detect phenotypically, ESBL producers in Gram negative isolates from different samples and to know their susceptibility pattern. A retrospective study of Gram negative isolates was conducted. Total of 521 isolates were isolated from various samples. They were processed and identified by standard procedures. The antibiotic susceptibility testing was performed by Kirby- Bauer disc diffusion method using CLSI guidelines. ESBL was detected by combination disk test. A total of 521 Gram negative isolates were isolated which included E. coli, Klebsiella pneumoniae, Citrobacter spp., Enterobacter spp., Proteus spp. and Acinetobacter spp. Pseudomonas aeruginosa. Of 521 isolates tested, ESBL was detected in 329 (63.1%) isolates. These isolates showed maximum susceptibility to piperacillin- tazobactam (86%) followed by imipenem (78.4%), amikacin (63.5%), cotrimoxazole (54.4%), ciprofloxacin (51%), amoxi-clav (44.9%), cefepime (44.1%), gentamicin (38.9%), cefoxitin (34.9%) and ampicillin (19.1%). ESBL producers which are resistant to beta lactam antibiotics have become a major problem. Detection of these beta-lactamase enzymes by simple disk method and its reporting will help clinicians in prescribing proper antibiotics.

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Prevalence of Extended Spectrum Beta-lactamase (ESBL) producing Enterobacteriaceae from clinical samples in a tertiary care hospital in Mumbai

Patel¹,

Jangla²,

Pillai³

et al. 2019

IJMR

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Study on Phenotypic Detection of Esbl in Gram Negative Bacterial Isolates in a Tertiary Care Hospital in Bangalore

Cited by 3 publications

References 8 publications

Detection of ESBL and MBL Producing Gram Negative Bacilli from various Clinical Samples at a Tertiary Care Hospital

Detection of ESBL and MBL Producing Gram Negative Bacilli from various Clinical Samples at a Tertiary Care Hospital

ESBL Producers in Gram Negative Isolates from Clinical Samples

Prevalence of Extended Spectrum Beta-lactamase (ESBL) producing Enterobacteriaceae from clinical samples in a tertiary care hospital in Mumbai

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