High-precision, temperature control technology is currently an important research field in spacecraft thermal control. High-precision temperature control based on grading-structure and PID-feedback strategies determine by theoretical analysis and grading a thermal control experiment is proposed in this paper. A sensitivity analysis of the key parameters influencing temperature control precision is investigated. The key parameters mainly include the inner emissivity of the transition section ¾ t , outer emissivity of the central section ¾ c , effective emissivity from the transition section to the central section ¾ i/o , inner emissivity of the central section ¾ i , outer emissivity of the equipment ¾ eq , outer emissivity of the mounting plate ¾ d , electronic equipment power P e , and the conductivity coefficient of the equipment mounting insulation pad . Both the theoretical and experimental results show that the strategies developed during this research can achieve temperature control precision better than 0.05 o C (or «0.025 o C). Parameters ¾ t , ¾ eq , and ¾ d not only influence the temperature level, but also influence steady time. P e , ¾ c , and ¾ i only influence the temperature level. ¾ i/o not only influences the temperature level, but also influences temperature control precision. Thermal conductivity influences temperature level rather than temperature control precision because of the active temperature control of the mounting plate. This study provides a new method for the high-precision thermal control of equipment in spacecraft and specifies new directions for future research work.