Study on prevalence of nephropathy in type 2 diabetes mellitus patients and associated factors

Abstract

Background: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease and the care of patients with diabetes and DN contributes significantly to health care costs. The objective of this present study was to determine prevalence of nephropathy in type2 diabetes and associated factor.Method: The present cross sectional study was conducted on type 2 diabetic subjects who attended the outpatient and inpatient wards of medicine department in GSL General Hospital from November 2015 to April 2017. Protocol approval was taken from institutional ethical committee and Informed consent from the study subjects was taken.Result: In this study the overall prevalence of nephropathy in type 2 DM was 44.7% (67 cases). The prevalence of nephropathy was similar in both males (44.3%) and Females (45.1%). and significant association was not found between gender and nephropathy. On apply of chi-square test, association was not found to be statistically significant for Sex (p=0.9), and ECG (p=0.07), whereas association was found to be statistically significant for HbA1C (p=0.04), Dyslipidemia (p=0.006), and USG (p=0.001).Conclusion: There is significant evidence to support the conclusion that microalbuminuria or proteinuria in patients with diabetes is a potential risk factor not only for kidney function impairment but also a marker for high risk of cardiovascular complications.