Fuel is the lifeblood of the aviation industry. The pressing
need
to reduce carbon emissions calls for the adoption of sustainable aviation
fuels (SAFs) as a feasible alternative, particularly in the absence
of widespread hydrogen usage. SAFs with high energy density (HED)
hold great promise due to their favorable weight and volume characteristics.
This comprehensive review article delves into the history of aviation
fuel, essential requirements for aviation fuels, and the imperative
for SAF development, focusing on the power-to-liquid (PtL) pathway
to produce SAFs. It particularly concentrates on recent advancements
in the screening and design of new strained hydrocarbons as high-performance
SAFs. By utilizing machine learning (ML) techniques, potential strained
hydrocarbon or cycloalkane structures have been identified and optimized,
revealing superior potentials for energy content and other critical
properties that enhance the efficiency and performance of SAFs. The
review also provides a perspective with a forward-looking approach
and a route map in the development of new SAFs, including the exploration
of strain energy in cycloalkanes through quantum mechanical calculations,
the establishment of structure–property relationships for rational
design, and the need for a technoeconomic assessment (TEA) of their production. It further highlights
the potential new directions in SAF development.