Study on Screening Tests among the Blood Donors in Dhaka Medical College Hospital, Bangladesh

Abstract

Context: Most deaths caused by transfusion worldwide is due to transmission of infectious agents like Virus, Bacteria and Protozoa. The risk of disease transmission increases many fold if blood donor selection is inappropriate (such as blood from professional donor) and testing of all blood for transfusion is inadequate. Methods: The study was carried out in transfusion Medicine department of Dhaka Medical College Hospital from January to December 2009 to see the prevalence of HBV, HCV, HIV, Treponema pallidum and Malarial parasite among the donor. Results: The study was carried out on 21448 donors, among whom 4464 (20.81%) were voluntary and 16984 (79.19%) were relative donors. Among 21448 donors, 21081 (98.29%) were selected and 367 (1.71%) were rejected. Out of 21081 selected donors 4406 (20.9%) were voluntary donor and 16675 (79.1%) were relative donor. Out of 367 rejected 58 (15.8%) were voluntary and 309 (84.2%) were relative donor. On analyzing the 367 rejected cases, HBsAg positive 297 (80.93%), Anti HCV positive 38 (10.35%), Malarial Parasite positive 23 (6.27%), Treponema pallidum positive 9 (2.45%) and none found positive for HIV. Key words: Blood donor; Voluntary donor; Relative donor; Screening. DOI: 10.3329/jdmc.v19i1.6245 J Dhaka Med Coll. 2010; 19(1) : 16-18.

Frequency of Transfusion Transmitted Diseases among Tribal Population of Rangamati in Bangladesh

“…High frequency (90.6%) of HBsAg seropositivity (n=87) observed among all detected TTD (n=96) in our study was consistent with the result of studies done in several tertiary level hospitals of Bangladesh. [5][6][7] HBV infection is the commonest TTD in our country as per record. 8 National data of Bangladesh show a seroprevelance of 0.96% for HBsAg among blood donors.…”

“…8 In three Medical College Hospitals HBV prevalence was slightly higher(1.38 to 2.19%). [5][6][7] These mentioned studied were done among general bengali population.In Rangamati with 3.46% HBsAg seropositivityamong tribal population the prevalence was higher than the mentioned data.…”

“…This observed result is similar to separate studies done in Bangladesh. [3][4][5][6][7] Hepatitis C prevalence in five native studies ranged from 0.024 to 0.52%. [3][4][5][6][7] Present study result for HCV was 0.28%.…”

“…Prior studies in Bangladesh were done either in Medical College Hospitals, Bangabandhu Sheikh Mujib Medical University (BSMMU) or private blood donating organization. [3][4][5][6] We could find only one study done outside Dhaka city as reference. 7 Study population varied from voluntary donors to specific high risk groups ie.…”

Surface Antigen (HBsAg) Negative Hepatitis B virus in Bangladesh: Warrants the Screening for Blood Donors

“…1 Transfusion of blood & blood component as a specialized modality of patient management saves million of lives each year worldwide. 2 The microbial agents are transmissible by blood transfusion & can cause morbidity & mortality in recipients. The infectious agents may present in the blood for long periods, sometimes in high titers, stability in blood stored at 4ºC or lower, long incubation period before the appearance of clinical signs, asymptomatic phase or only mild symptoms in the blood donor, hence not identifiable during the blood donor selection process.…”