Study on single crystal structure of the antimony(III) bromide complex with 3-methyl-2-mercaptobenzothiazole and biological activity of some antimony(III) bromide complexes with thioamides

Öztürk, I.I.; Μέτσιος, Απόστολος; Filimonova-Orlova, S.; Kourkoumelis, Nikolaos; Hadjikakou, Sotiris K.; Manos, Manolis J.; Tasiopoulos, Anastasios J.; Karkabounas, Spyridon; Милаева, Е. Р.; Hadjiliadis, Nick

doi:10.1007/s00044-011-9905-9

Cited by 19 publications

(10 citation statements)

References 23 publications

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“…It is also notable that antimony(III) complexes exhibit strong anti-proliferative activity against human cancer cells, (HeLa and Molt4/C8 cells) especially to HeLa and not to murine cells. Moreover the antimony bromide complexes show selectivity activity against both sarcoma (LMS) and carcinoma (HeLa) cells [8][9][10][11][12][13]. In conclusion the dimeric geometry or the ionic nature of the compounds affects their biological activity ( Table 2).…”

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 95%

“…The inhibitory effects of antimony(III) halide complexes 2-31 on the in vitro proliferation of Murine Leukemia Cells (L1210), Murine Mammary Carcinoma Cells (FM3A), Human T-lymphocyte Cells (Molt4/C8, CEM) and Human Cervix Carcinoma Cells (HeLa) were evaluated [8][9][10][11][12]. Moreover antimony(III) bromide complexes 8-17 were also evaluated against leiomyosarcoma cells (LMS) [11] (Table 2).…”

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 99%

“…The antimony(III) complexes with S atom donor ligands (L_S) isolated, are divided according to the starting materials used for their preparation SbCl 3 , SbBr 3 and SbI 3 [8][9][10][11][12] [8][9][10][11][12]. All Sb(III) complexes were characterized by elemental analysis, FT-IR, far-FT-IR, differential thermal analysis-thermogravimetry, X-ray diffraction, and conductivity measurements.…”

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 99%

“…Moreover antimony(III) bromide complexes 8-17 were also evaluated against leiomyosarcoma cells (LMS) [11] (Table 2). Among the cell lines tested (L1210, FM3A, Molt4/C8, CEM and HeLa) antimony halide compounds 2-31 show selectivity against HeLa cells.…”

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 99%

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Recent advances on antimony(III/V) compounds with potential activity against tumor cells

Hadjikakou

Öztürk

Banti

et al. 2015

Journal of Inorganic Biochemistry

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Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 95%

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 99%

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 99%

Section: Antimony Complexes Of Thiones/thioles Ligandsmentioning

confidence: 99%

See 2 more Smart Citations

Recent advances on antimony(III/V) compounds with potential activity against tumor cells

Hadjikakou

Öztürk

Banti

et al. 2015

Journal of Inorganic Biochemistry

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“…melglumineantimoniate (Glucantime) and sodium stibogluconate (Pentostam)) [9]. The potential anticancer activity of antimony compounds is under consideration [9][10][11][12][13][14][15][16][17][18][19][20][21][22]. The last studies indicated that antimony(III) compounds are more active against carcinoma than lymphoma [17].…”

Section: Introductionmentioning

confidence: 99%

Novel Antimony(iii) Halide Complexes With Some N-Alkyl Thioureas: Synthesis, Characterization and Study of Their Effect Upon the Catalytic Oxidation of Linoleic Acid to Hydroperoxylinoleic Acid by Lipoxygenase

Öztürk

2016

J. Turk. Chem. Soc., Sect. A: Chem.

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C) spectroscopy and TG-DTA analysis. The reactions of N-methylthiourea (NMTU) and N-ethylthiourea (NETU) with SbX3 (X = Cl or Br) in a 2:1 ligand/metal rate but unexpected products were formed in a 3:1 ligand/metal rate. The compounds are non-electrolytes in solution and spectroscopic data of the compounds are appropriate with six coordinate octahedral geometry by three halide ions and three sulfur atoms from thiourea ligands. N-methythiourea and N-ethylthiourea ligands behave as monodentate in compounds 1-4 with the binding through sulfur. The influence of these compounds 1-4, N-methythiourea and N-ethylthiourea upon the catalytic peroxidation of linoleic acid to hyperoxolinoleic acid by lipoxygenase was kinetically studied.

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Synthesis, Characterization, and Biological Investigation of Antimony(III) Halide Complexes With Different Coordination Architectures Constructed From Thiophene Thiosemicarbazones

Ucar,

Ozturk,

Grześkiewicz

et al. 2024

Applied Organom Chemis

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In this study, we report the synthesis, characterization, and biological investigation of antimony(III) halide complexes with various coordination architectures constructed from thiophene thiosemicarbazones. Antimony(III) thiophene‐2‐carbaldehyde thiosemicarbazone complexes (1, 2, 4, and 5) exhibit a square pyramidal geometry, with ligands coordinated to the central antimony atom in two distinct binding modes. In contrast, antimony(III) 2‐acetylthiophene thiosemicarbazone complexes (3, 6, and 7) adopt a seesaw geometry. These complexes (1–7) represent the first reported examples of antimony(III) halide thiosemicarbazone compounds. The unique coordination environments observed in these complexes are of significant importance within the realm of antimony chemistry. These synthesized complexes exhibit different coordination geometries as well as potential biological activities. The antiproliferative activity against the human breast adenocarcinoma (MCF‐7) cell line and antimicrobial activity against Gram‐positive and Gram‐negative bacteria were assessed. Antimony(III) thiophene‐2‐carbaldehyde thiosemicarbazone complexes (1, 2, 4, and 5) showed significant antiproliferative activity with IC50 values ranging from 8.5 to 19.1 μM, while antimony(III) 2‐acetylthiophene thiosemicarbazone complexes (3, 6, and 7) had higher IC50 values. Additionally, the antimony complexes demonstrated selective antimicrobial activity against Gram‐negative bacteria.

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Study on single crystal structure of the antimony(III) bromide complex with 3-methyl-2-mercaptobenzothiazole and biological activity of some antimony(III) bromide complexes with thioamides

Cited by 19 publications

References 23 publications

Recent advances on antimony(III/V) compounds with potential activity against tumor cells

Recent advances on antimony(III/V) compounds with potential activity against tumor cells

Novel Antimony(iii) Halide Complexes With Some N-Alkyl Thioureas: Synthesis, Characterization and Study of Their Effect Upon the Catalytic Oxidation of Linoleic Acid to Hydroperoxylinoleic Acid by Lipoxygenase

Synthesis, Characterization, and Biological Investigation of Antimony(III) Halide Complexes With Different Coordination Architectures Constructed From Thiophene Thiosemicarbazones

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