2023
DOI: 10.1016/j.canep.2023.102333
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Study on TFF1 and PALB2 gene variants associated with gastric carcinoma risk in the Chinese Han population

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“…The genetic variant rs249954 C > T exhibits functional effects, including altered enhancer histone marks, changed motifs, and signi cant associations with phenotypes as observed in NHGRI/EBI GWAS hits and GRASP QTL hits [23]. Moreover, the rs152451 A > G single nucleotide polymorphism (SNP) in the PALB2 gene is positioned proximal to the exon 4 splice donor site.…”
Section: Introductionmentioning
confidence: 99%
“…The genetic variant rs249954 C > T exhibits functional effects, including altered enhancer histone marks, changed motifs, and signi cant associations with phenotypes as observed in NHGRI/EBI GWAS hits and GRASP QTL hits [23]. Moreover, the rs152451 A > G single nucleotide polymorphism (SNP) in the PALB2 gene is positioned proximal to the exon 4 splice donor site.…”
Section: Introductionmentioning
confidence: 99%