Study on the Association between Domestic Biomass Fuel Exposure and Pulmonary Function: A Systematic Review and Meta-Analysis

Viramgami, Ankit; Sheth, Ankit; Bagepally, Bhavani Shankara; Balachandar, Rakesh

doi:10.2139/ssrn.4267517

SSRN Journal

2022

DOI: 10.2139/ssrn.4267517

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Study on the Association between Domestic Biomass Fuel Exposure and Pulmonary Function: A Systematic Review and Meta-Analysis

Ankit Viramgami

Ankit Sheth

Bhavani Shankara Bagepally

et al.

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“…On the one hand, several epidemiological studies have found associations between biomass smoke exposure and COPD with odds ratios of 2 or more. [68][69][70][71] On the other hand, other studies, including the BOLD study and others done in Malawi, found no association between airflow obstruction and exposure to biomass. 4,35,72 For this study, the sample size was not powered to determine the differences between the cases and the comparison group due to the high use of biomass fuel.…”

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confidence: 79%

Prevalence and Associated Factors of Chronic Obstructive Pulmonary Disease Among Adults in Neno District, Malawi: A Cross-Sectional Analytical Study

Zaniku,

Connolly,

Aron

et al. 2024

COPD

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Chronic obstructive pulmonary disease (COPD) continues to pose a global public health challenge. However, literature is scarce on the burden of COPD in Malawi. We assessed the prevalence and risk factors for COPD among adults in Neno, Malawi. Methodology: We conducted a population-based analytical cross-sectional study in Neno District between December 2021 and November 2022. Using a multi-stage sampling technique, we included 525 adults aged≥40 years. All participants underwent spirometry according to the American Thoracic Society (ATS) guidelines and were interviewed using the IMPALA questionnaire. For this study, we utilized the definition of COPD as a post-bronchodilator FEV1/FVC <0.70. We collected data using Kobo collect, exported to Microsoft Excel, and analysed using R software. We used descriptive statistics and logistic regression analysis; a p-value of <0.05 was considered statistically significant. Results: Out of 525 participants, 510 participants were included in the final analysis. Fifty-eight percent of the participants were females (n=296), and 62.2% (n=317) were between 40 and 49 years with a median (IQR) age of 46 (40-86). For patient characteristics, 15.1% (n=77) were current smokers, and 4.1% (n=21) had a history of pulmonary tuberculosis (PTB). Cough was the most commonly reported respiratory symptom (n=249, 48.8%). The prevalence of COPD was 10.0% (n=51) and higher (15.0%) among males compared to females (6.4%). Factors significantly associated with COPD were age 60 years and above (adjusted odds ratio [aOR]

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