Study on the effect of acupunture treatment on autonomic nerve dysfunction in convalescent period of stroke based on heart rate variability assessment technique

Abstract

Stroke patients with autonomic dysfunction are more likely to develop cardiac problems, which have been linked to lower functional outcomes and increased mortality. In this study, heart rate variability (HRV) detection paired with the Clinical Feature Scale will be utilized to elucidate the immediate impact of manual acupuncture on autonomic dysfunction of varying severity in the convalescence stroke phase. This is a randomized, single-blind, controlled clinical trial approach. At a ratio of 1:1, 60 appropriate patients will be randomly randomized into either the experimental or control group. On the basis of symptomatic treatment drugs, the experimental group will additionally undertake acupuncture therapy 3 times a week for 4 weeks, for a total of 12 times. Primary outcomes include 24-hour HRV and 60-minute HRV detection at week 4 compared with baseline. The secondary outcome is the score of clinical feature scale at week 4 compared with the baseline. Adverse events and safety indices will be recorded throughout the experiment. The SPSS V.25.0 statistical program was applied for analysis, and measurement data were expressed as mean ± SD.

Acupuncture for ischemic stroke: Where are we now?

“…Several randomized controlled trials (RCTs) have been conducted on electroacupuncture (EA) and manual acupuncture stimulation. Although the duration and frequency of interventions vary, these results support the clinical efficacy of acupuncture in improving motor dysfunction after IS [22,39–41,44–48] . In particular, acupuncture may improve patients’ National Institute of Health stroke scale (NIHSS) scores and the ability to perform activities of daily living.…”

The Effect of Stress-Reducing Interventions on Heart Rate Variability in Cardiovascular Disease: A Systematic Review and Meta-Analysis

“…Characteristics of the included ongoing studies [ 43 , 44 , 45 , 46 , 47 , 48 , 49 ] and the studies without accessible/published results [ 50 , 51 , 52 , 53 , 54 ] are shown in Tables S2 and S3 of the Supplementary Materials .…”

“…The characteristics of the included studies with published results are presented in Table 1. Characteristics of the included ongoing studies [43][44][45][46][47][48][49] and the studies without accessible/published results [50][51][52][53][54] are shown in Tables S2 and S3 of the Supplementary Materials.…”