Study on the effective ablation volume of microwave ablation of porcine livers

Abstract

This paper reports on an effective ablation volume model for microwave ablation of porcine liver. Firstly, in order to obtain the temperature field distribution, a theoretical simulation model of the microwave ablation of porcine liver was developed by solving Pennes bioheat transfer equation using the COMSOL Multiphysics software. Then the effective ablation volume and the effective ablation volume model were obtained using the 1stOpt fitting software by 7D-Soft High Technology Inc. (China). Finally, microwave ablation experiments were carried out using porcine liver to verify the accuracy and effectiveness of the model. The results show that according to the ablation volume model, one can determine the scope of the effective ablation under varying conditions of microwave power and duration. This provides an important basis for the preoperative planning system of microwave ablation. Zusammenfassung: Die vorliegende Arbeit berichtet über ein effektives Ablationsvolumen-Modell für die Mi krowellenablation von Schweineleber. Zuerst wurde ein theoretisches Simulationsmodell durch Lösen der BioWärmetransfer-Gleichung von Pennes unter Verwendung der COMSOL Multiphysics Software entwickelt, um die Temperatur-Feldverteilung in Schweineleber zu ermitteln. Danach wurde das effektive Ablationsvolumen durch ein Ablationsvolumen-Modell unter Verwendung der 1stOpt Fitting-Software (7D-Soft High Technology Inc., China) bestimmt. Schließlich wurden Mikrowellenablations-Experimente mit Schweineleber durchgeführt, um die Genauigkeit und Effektivität des Modells zu über-prüfen. Die Ergebnisse zeigen, dass unter Zugrundelegung des Ablationsvolumen-Modells der Umfang der effektiven Ablation unter variierenden Bedingungen von Mikrowellenleistung und Applikationsdauer bestimmt werden kann. Dies stellt eine wichtige Grundlage für ein präoperatives Planungssystem der Mikrowellenablation dar.

Medical use of lasers and photonics in Russia – Therapeutic applications

“…With respect to the applied energy sources, radiofrequency [27,28] and interstitial laser therapy [29,30] as well as microwave ablation [31] are in use, whereas treatment-planning models are still a matter of debate. Hu et al [32] report on an effective ablation volume model for microwave ablation in liver tissue. This simulation model, based upon the Pennes bioheat transfer equation, was developed and compared with tissue experiments to assess its accuracy and effectiveness and can be regarded as being an important step in the pre-operative treatment planning of microwave ablation.…”