Natural gas is a promising alternative fuel for internal combustion engines, it allows for a reduction of engine-out emissions without impairing high engine efficiencies. Although this approach is already utilized from small to large engine classes, it is almost exclusively based on the combustion of a premixed homogeneous charge. For ignition, small engines use standard spark plugs or pre-chambers, while large and lean-operated engines use pre-chambers and pilot injections. Direct high-pressure gas injection is a more recent, alternative way to operate gas engines which offers benefits compared to premixed operation such as high combustion pressures, leaner operation, easier quantity regulation, and higher compression ratios, among others. However, in contrast to diesel injection, the compression temperatures are too low for the auto-ignition of the gas jets. Therefore, an additional ignition system is required, usually a pilot injection system is used. In this study, the usability and performance of a scavenged pre-chamber used for the ignition a high-pressure gas jet has been investigated in an optically accessible test-rig that is able to operate at engine-like conditions. Results show that the turbulent hot jet generated by the pre-chamber was able to ignite the high-pressure gas jet under a wide range of operating conditions. Moreover, it also appears to be a promising ignition strategy for very early direct injection during the compression stroke as well as for port injection. The good performance is attributed to the intense mixing of the main gas jet with the hot jet exiting the pre-chamber.