Study on the Influencing Factors of Short‐Term Recovery of Neurological Symptoms after Carotid Body Tumor Resection

Abstract

Objective To compare the differences in the short-term recovery from neurological symptoms (SRN) (B 6 months) and clinical characteristics of patients with different Shamblin classifications carotid body tumor (CBT) resection and to analyze the risk factors affecting SRN after surgery. Methods Patients who underwent CBT resection between June 2018 and September 2022 were recruited. Perioperative factors and indicators of the nature of the tumor were recorded. The risk factors affecting SRN after CBT resection were analyzed using logistic regression analysis. Results Eighty-five patients (43.86 ± 12.7 years, 46 females) were included, 40 (47.06%) of whom exhibited SRN. Univariate logistic regression showed that preoperative symptoms, surgical side, bilateral posterior communicating artery (PcoA) opening, some indicators of tumor size, operative/anesthesia time, and Shamblin III classification were correlated with postoperative neurological prognosis (all p \ 0.05). After adjusting for confounders, preoperative symptoms (OR, 5.072; 95% CI 1.027-25.052; p = 0.046), surgical side (OR, 0.025; 95% CI 0.003-0234; p = 0.001), bilateral PcoA opening (OR, 22.671;; p = 0.005), distance from the tip of the C2 dens to the superior aspect (dens-CBT) (OR, 0.918; 95% CI 0.858-0.982; p = 0.013) and Shamblin III classification (OR, 28.488;; p = 0.014) were correlated with postoperative neurological symptom recovery. Conclusion Preoperative symptoms, surgical side (right), bilateral PcoA opening, a short dens-CBT and Shamblin III classification are risk factors affecting SRN after CBT resection. Early resection is recommended for small-volume CBTs without neurovascular compression or invasion to obtain SRN.

Novel insights into the classification of Shamblin III carotid body tumors from a neurosurgical perspective

“…The main postoperative complications included neurological dysfunction (hoarseness, loss of voice, choking, tongue extension deviation, and Horner syndrome), neck hematoma, wound infection, tumor recurrence, and cerebrovascular accidents. Long-term complications have been described in our previous study [ 13 ].This present study only considered the short-term complications immediately after surgery.…”

“…Our team has one of the largest annual cohorts of CBT operations in China. We previously analyzed the risk factors for neurological symptoms after CBT resection in our patients [ 13 ]. In this study, we aimed to further clarify the specific arterial forms within tumors and demonstrate the varied anatomic differences between III-CBTs.…”