Study on the removal of benzisothiazolinone biocide and its toxicity: The effectiveness of ozonation

Li, Ang; Chen, Zhuo; Wu, Qian-Yuan; Huang, Manhong; Liu, Zi-Ye; Chen, Ping; Mei, Lin-Chun; Hu, Hong-Ying

doi:10.1016/j.cej.2016.04.021

Cited by 46 publications

(18 citation statements)

References 42 publications

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“…Benzisothiazolinone (BIT) has been described as being hydrolytically stable, presenting a half-life of more than 30 days in the environment [73]. BIT may be transported through soil and reach surface water, and it can still retain its biocidal qualities for 3 months when exposed to sunlight [73,74]. Wang et al evaluated the photodegradation of BIT by UVC irradiation and verified the influence of several parameters, including initial BIT concentration, solution pH, and HCO 3 − anion [75].…”

Section: Stability Of Isothiazolinonesmentioning

confidence: 99%

“…The first-order photolysis rate constant was determined to be 0.019 d −1 for MCI at pH 4 [6]. Benzisothiazolinone (BIT) has been described as being hydrolytically stable, presenting a halflife of more than 30 days in the environment [73]. BIT may be transported through soil and reach surface water, and it can still retain its biocidal qualities for 3 months when exposed to sunlight [73,74].…”

Section: Stability Of Isothiazolinonesmentioning

confidence: 99%

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Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

et al. 2020

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The importance of isothiazole and of compounds containing the isothiazole nucleus has been growing over the last few years. Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic and fungiostatic activity. Despite their effectiveness as biocides, isothiazolinones are strong sensitizers, producing skin irritations and allergies and may pose ecotoxicological hazards. Therefore, their use is restricted by EU legislation. Considering the relevance and importance of isothiazolinone biocides, the present review describes the state-of-the-art knowledge regarding their synthesis, antibacterial components, toxicity (including structure–activity–toxicity relationships) outlines, and (photo)chemical stability. Due to the increasing prevalence and impact of isothiazolinones in consumer’s health, analytical methods for the identification and determination of this type of biocides were also discussed.

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Section: Stability Of Isothiazolinonesmentioning

confidence: 99%

Section: Stability Of Isothiazolinonesmentioning

confidence: 99%

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

et al. 2020

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“…Once the reaction time exceeded 15 min, the COD removal efficiency increased to 10%, while the COD removal efficiency increased to 28% after 30 min of reaction. The reaction rate of the ozonation process is mainly limited by the transfer step in the early stage of the reaction (Li et al 2016a); with the increase in reaction time, a certain amount of O 3 was dosed and more •OH appeared; thus, a corresponding number of target organic compounds were degraded.…”

Section: Role Of Ozone and Mn Ore Tailing In The Combined Oxidation Processesmentioning

confidence: 99%

High increase in biodegradability of coking wastewater enhanced by Mn ore tailings in Fenton/O3 combined processes

Liu

et al. 2020

Int. J. Environ. Sci. Technol.

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Coking wastewater contains high concentration of organic pollutants and seriously endangers the natural ecological balance and human health. This study proposes a novel pre-treatment method that can significantly improve removal efficiency of organic pollutants in coking wastewater by the concept of "treating waste with waste." Three two-step advanced oxidation processes were proposed by combining Fenton, ozonation with manganese tailings: (i) O 3 /Mn tailings + H 2 O 2 , (ii) O 3 /Mn tailings + Fenton and (iii) Fenton + O 3 /Mn tailings. Results show that (1) Fenton + O 3 /Mn tailings presented the best removal efficiency in the three combined processes. The reaction process was carried out by first performing Fenton reaction on the wastewater for 65 min, and then, the reaction wastewater was subjected to ozone and manganese tailings mixed reaction for 30 min, and the chemical oxygen demand (COD) and chromaticity were reduced by 61.0% and 96.1%, respectively. (2) After pre-treated with Fenton, the biodegradability of the wastewater can be significantly increased. When Fenton + O 3 /Mn ore tailings were used to pre-treat the raw water, the biodegradability (BOD 5 /COD) of the wastewater was increased to 0.54. It is proved that the combined process Fenton + O 3 /Mn ore tailings has better performance than the ordinary single advanced oxidation process. Compared with the existing methods, the addition of manganese tailings containing manganese oxides as catalytic free radicals can significantly improve the treatment activity of advanced oxidation process (AOPS).

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“…Isothiazolones can pass through cell membranes and fungal cell walls, after which they conduct nucleophilic attack of intracellular sulfur atoms in biomolecules such as proteins and small molecules, to impair cell functions [7]. For instance, 1,2-benzisothiazol-3(2H)-one (BIT) is highly toxic to zebrafish embryos [8], and BIT can inhibit the activity of enzymes such as phosphatases [9]. Moreover, a CMIT/MIT mixture can cause allergic reactions, and the halogenated groups induce CMIT sensitization [1].…”

Section: Introductionmentioning

confidence: 99%

Adsorption of Isothiazolone Biocides in Textile Reverse Osmosis Concentrate by Powdered Activated Carbon

Chen

Wang

et al. 2018

Water

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Isothiazolones have been widely applied as non-oxidizing biocides to prevent biofouling of reverse osmosis (RO) membranes. However, few studies have investigated suitable RO concentrate treatments to remove these biocides. This study evaluated the adsorption behavior of four isothiazolone biocides, 2-methyl-4-isothiazolin-3-one (MIT), 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), 1,2-benzisothiazol-3(2H)-one (BIT), and 2-n-octyl-4-isothiazolin-3-one (OIT), by powdered activated carbon (PAC). Isothiazolones adsorption was found to obey pseudo second-order kinetics. Langmuir adsorption isotherms were more suitable to simulation of the adsorption effects than Freundlich isotherms. The adsorption amount followed the order OIT > BIT > CMIT > MIT, in accordance with the isothiazolones octanol/water partition coefficients (K ow), indicating that hydrophobicity is the main factor for influencing adsorption amounts. Following normalization with K ow , the amounts of isothiazolones adsorbed at equilibrium and normalized aqueous concentrations showed a linear relationship in a log-linear form. 1,2-benzisothiazol-3(2H)-one is anionic at high pH, and difficult to adsorb, while neutral BIT is more likely to be adsorbed. Textile reverse osmosis concentrate had an adverse effect on MIT, CMIT and BIT adsorption, but little effect on adsorption of OIT, which has a high log K ow value. There was competition between organics and isothiazolones for PAC adsorption sites, which influenced the adsorption efficiency.

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Study on the removal of benzisothiazolinone biocide and its toxicity: The effectiveness of ozonation

Cited by 46 publications

References 42 publications

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles

High increase in biodegradability of coking wastewater enhanced by Mn ore tailings in Fenton/O3 combined processes

Adsorption of Isothiazolone Biocides in Textile Reverse Osmosis Concentrate by Powdered Activated Carbon

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