In traditional ecological scheduling, a single monthly or daily model will lead to the incomplete transmission of ecological information or increase the complexity of solving problems. Therefore, a multi-timescale nested model (MTNM) is proposed. Although the MTNM can express the daily flow process of environmental flow, the quadratic nested calculation method cannot obtain the optimal solution for the daily scheduling scheme. Targeting the problem that long and short-term objectives cannot obtain the optimal solution at the same time, this paper proposes a multi-timescale integrated model (MTIM) which considers the monthly, 10-day, and daily scale. The model is applied to the Liujiaxia reservoir. The scheduling results show that, compared with the MTNM, the MTIM can better meet the multi-objective demand. In a wet year, when both models can guarantee water supply and ecological demand, the MTIM increases electricity generation by 0.91%. In a dry year, electricity generation can still be increased by 4.35% without sacrificing the ecological and water supply benefits of the lower reaches. In different typical years, the MTIM can improve the contradictory relationship between multi-objective by improving the utilization efficiency of water. The results can improve the decision support for the operation process of other reservoirs with ecological needs.