Study on the transfer of components of Aetheroleum carvi and Aetheroleum foeniculi oils

Lado, C.; Hajdú, Melinda; Farkas, Edit; Then, M.; Taba, Gabriella; Szentmihályi, Klára

doi:10.1016/j.fitote.2004.11.005

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…In various studies the essential oil yields ranged from 0.47% to 7.00% (2,4,17,21,28,(31)(32). Carvone and limonene have been mentioned as the main essential oil constituents (2,4,10,12,14,16,17,19,21,24,26,27,(30)(31).…”

Section: Introductionmentioning

confidence: 99%

The content and composition of the essential oil Found inCarum carviL. commercial fruits obtained from different countries

Raal

Arak

Orav

2012

Journal of Essential Oil Research

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Caraway (Carum carvi L., Apiaceae) is a very popular spice and herb, which is widely applied in the food and pharmaceutical industry. Variations in the essential oil content and composition in twenty commercial caraway samples obtained from retail pharmacies and health shops in different countries were determined using hydrodistillation and capillary GC techniques. The essential oil yields ranged from 0.6% to 5.4%. Eighteen compounds, comprising more than 97% of the composition of oil, were identified in the caraway essential oils. The main components of the oils in caraway seeds were carvone (44.5-95.9%) and limonene (1.5-51.3%). Between the content of carvone and limonene the negative correlation -0.999 (p<0.01) was found. Additionally, b-myrcene (0-0.4%), trans-dihydrocarvone (0-0.5%), and trans-carveole (0-0.2%), as well as a-pinene, sabinene, n-octanal, trans-b-ocimene, c-terpinene, linalool, cis-and trans-limonene oxide, cis-dihydrocarvone, cis-carveol, perillaldehyde, trans-anethole, and trans-b-caryophyllene were found in caraway oils. The content and composition of the essential oils in commercial caraway seeds is remarkably variable and conformed with the European Pharmacopoeia standards only in four samples among the 20 commercial caraway samples studied. The carvone and carvone-limonene chemotypes were found.

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Section: Introductionmentioning

confidence: 99%

The content and composition of the essential oil Found inCarum carviL. commercial fruits obtained from different countries

Raal

Arak

Orav

2012

Journal of Essential Oil Research

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Element determination in volatile oil containing fennel (Foeniculum vulgare) by ICP-OES and polarography

Ladó¹,

Then²,

May³

et al. 2007

Acta Alimentaria

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Comparative study of Two In Vitro Methods for Assessing Drug Absorption: Sartorius SM 16750 Apparatus Versus Everted Gut Sac

Lassoued

Khemiss²,

Sfar³

2011

J Pharm Pharm Sci

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-Purpose. Oral drug administration remains the most common and most convenient way used in clinical therapy. The availability of a simple, rapid, economic and reproducible in vitro method to assess the rate, extent and mechanism of intestinal drug absorption is a very helpful tool. The purpose of this study was to compare the performance of Sartorius SM 16750 Absorption Simulator apparatus to Everted Gut Sac (EGS) technique in terms of predicting drug permeability. Methods. Permeation studies across these two in vitro models were performed with six drugs selected across the Biopharmaceutics Classification System (BCS) categories: tramadol (class I of BCS), doxycycline (class I of BCS), diclofenac (class II of BCS), clopidogrel (class II of BCS), metformin (class III of BCS) and chlorothiazide (class IV of BCS). Results. Apparent permeability coefficient (P app ) and diffusion profiles obtained with EGS and Sartorius SM 16750 apparatus were similar for diclofenac and metformin, whereas, we noticed significant differences (p≤0.05), for tramadol, doxycycline, clopidogrel and chlorothiazide. Conclusion. Compared to Everted Gut Sac model, Sartorius SM 16750 absorption simulator apparatus seems to have limited application for the assessment of intestinal drug absorption since it does not take into consideration the involvement of others processes than the passive transcellular pathway as mechanism of drug absorption. _______________________________________________________________________________________

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Study on the transfer of components of Aetheroleum carvi and Aetheroleum foeniculi oils

Cited by 3 publications

References 17 publications

The content and composition of the essential oil Found inCarum carviL. commercial fruits obtained from different countries

The content and composition of the essential oil Found inCarum carviL. commercial fruits obtained from different countries

Element determination in volatile oil containing fennel (Foeniculum vulgare) by ICP-OES and polarography

Comparative study of Two In Vitro Methods for Assessing Drug Absorption: Sartorius SM 16750 Apparatus Versus Everted Gut Sac

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