Study The Pharmacologic Effect Of Both Gonadotropins And Letrozole On The Level Of Serum Glycoproteins (Inhibin B, Amh, And Hrg) In Infertile Women And Their Effect On Stimulating Ovulation

Abstract

Objective: To see how letrozole and gonadotropin alter the levels of serum glycoproteins (HRG, AMH, and Inhibin B) .Methods: As a control group, 33 infertile women and 22 healthy (fertile women) were recruited from an outpatient women's clinic (OWC). They are between the ages of ( 50) and ( 44). HRG, inhibin B, and AMH glycoproteins were evaluated using the ELISA technique.Results: According to a research that evaluated the blood levels of inhibin B, AMH, and HRG in infertile and healthy women, Infertile women's serum inhibin B levels are substantially lower than healthy women's (p = 0.05). Despite the fact that HRG and AMH concentrations were not significantly different (p > 0.05), the quantity and size of oocytes increased significantly (p = 0.000) in both the right and left ovarian infertile women after therapy as compared to the infertile ladies who were infertile before therapy.Conclusion: Letrozole and gonadotropin medicines have an effect on HRG and AMH levels in infertile women after treatment.