Studying Healthy Psychosislike Experiences to Improve Illness Prediction

Abstract

ImportanceDistinguishing delusions and hallucinations from unusual beliefs and experiences has proven challenging.ObservationsThe advent of neural network and generative modeling approaches to big data offers a challenge and an opportunity; healthy individuals with unusual beliefs and experiences who are not ill may raise false alarms and serve as adversarial examples to such networks.Conclusions and RelevanceExplicitly training predictive models with adversarial examples should provide clearer focus on the features most relevant to casehood, which will empower clinical research and ultimately diagnosis and treatment.