Studying some possible irritable bowel syndrome manifestations in COVID-19 patients

Ilie, Ovidiu-Dumitru; Nita, Ilinca-Bianca; Cojocariu, Roxana-Oana; Balmuș, Ioana-Miruna; Ciobîcă, Alin; Doroftei, Bogdan; Trifan, Anca; Stanciu, C

doi:10.22551/msj.2021.02.04

Cited by 1 publication

(1 citation statement)

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“…Zanini et al achieved similar conclusions about the development of IBS following an outbreak of viral gastroenteritis caused by drinking water (38). Following the coronavirus pandemic in 2019 and reports of IBS-like symptoms in some patients, as well as exacerbating the symptoms of previous IBS patients, the hypothesis of possible viruses contributing to IBS has been strengthened, although some researchers have linked these changes to stress and fear of being infected with the virus (39)(40)(41)(42). Rotavirus is a genus of the Reoviridae family.…”

Section: Discussionmentioning

confidence: 88%

Association between Rotavirus Infection and Irritable Bowel Syndrome: A Case-Control Study in Kerman, Iran

Aalipour,

Zahedi,

Zangouey

et al. 2023

Journal of Kerman University of Medical Sciences

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Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal disease of unknown etiology. Researchers have recently drawn attention to the possible role of viruses in the development of IBS and provided evidence in this regard. In this study, it was decided to investigate the possible role of rotavirus infection in the onset of IBS. Methods: Stool and serum samples were collected from 40 patients with IBS and 40 healthy individuals. To evaluate the previous exposure to rotavirus we checked the presence and concentration of anti-rotavirus IgG by ELISA. ELISA test was performed on the serum samples. A real-time polymerase chain reaction (PCR) test was also used to measure the viral load in the stool. Finally, the data were analyzed by SPSS version 22 software. Results: No significant relationship was found between anti-rotavirus IgG presence and its level in the serum of case and healthy individuals (P value>0.05). Moreover, there was no significant difference between the viral genome load in the stool samples of the two groups (P value>0.05). Conclusion: According to the results, it seems unlikely that a link exists between rotavirus infection and the onset of IBS, but the possible role of other gastrointestinal viruses, including coronavirus, remains.

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