The rapid growth in subscribers and usage of multimedia services enlarges the volume of Session Initiation Protocol (SIP) call control signalling creating a need to understand Quality of Experience (QoE) in this case and improve it. This paper provides an analysis of influence of SIP call control signalling on QoE for Voice over Internet Protocol (VoIP) service. The aim was to investigate whether SIP call control signalling load has the influence on the human perception of SIP signalling performances and QoE, and to identify the importance of distinct SIP-based signalling performance metrics. Moreover, the intention was to determine whether SIP call control signalling load changes its impact if previously proposed algorithm for differentiated treatment of SIP messages is activated, and quantify mutual relationships of considered user perceptions and QoE. The findings show that SIP call control signalling load has a strong and negative impact on dependent variables and that the proposed algorithm improves QoE and human perception of SIP signalling performances.