The ban on girls’ education or difficult access to education has significant impacts on their mental health and quality of life (QoL), including: (a) Increased Mental Health Problems; (b) Loss of Educational Opportunities; (c) Limited Social Interaction; (d) Disruption of Aspirations and Routines; and (e) Increased Insecurity. This study extends the investigation into the need for awareness and action on the mental health and well-being of girls due to the ban or difficult access to education. Addressing the adverse impacts of the ban or difficult access to girls’ education requires a multifaceted approach that includes challenging traditional norms, providing alternative education pathways, empowering girls through targeted interventions, and recognizing the critical role of education.