Stupor, Hypercalcemia and Carcinoma of the Renal Pelvis

The Systemic Effects of Malignant Renal Tumours1

“…However, in the absence of bony involvement or other abnormalities the possibility arises that the tumour itself is responsible for the excess hormone and produces pseudohyperparathyroidism. Pseudohyperparathyroidism is most commonly associated with carcinoma of the bronchus or renal cell carcinoma (30 per cent) but may occur with carcinoma of the liver, breast, pancreas, ovary and, rarely, with squamous carcinoma of the renal pelvis (Bourne et al, 1964;Goldberg et al, 1964). The differential diagnosis of hypercalcaemia encompasses a wide range of conditions though many of these may readily be excluded.…”

Hypercalcemia Associated with Transitional Cell Carcinoma without Bone Metastases: Description of Two Cases

“…Of these tumors 4 were epidermoid carcinoma [5][6][7][8][9], 3 were squamous cell carcinoma [5,10,11], and 6 were transitional cell carci noma [12][13][14][15]. Squamous cell carcinoma accounts for about 15% of all bladder tumors with about 76% of tran sitional cell carcinoma [16], It is possible that squamous cell carcinomas are more commonly involved in releas ing hypercalcémie factor similar to the finding by Bender and Hansen [ 17] in bronchogenic carcinoma.…”

Hypercalcemia in Upper Urinary Tract Urothelial Carcinoma: A Case Report and Literature Review

“…The cases with a suppressed PTH without an elevation of PTHrP [9, 16, 21, 22, 25] could have been from an elevated 1,25-dihydroxyvitamin D if it had been measured. Some other cases [3, 11, 26] might have proven an elevated 1,25-dihydroxyvitamin D, if the full workup was available. …”