Sub Clinical Disease Presenting with Serious Clinical Manifestations - Blame Thyroid

Talwar, Dhruv; Kumar, Sunil; Garikapati, Amrutha; Chaturvedi, Anuj

doi:10.14260/jemds/2020/518

Cited by 10 publications

(10 citation statements)

References 4 publications

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“…Treatment of overt thyroid malfunction typically resolves concomitant mood and cognitive problems, however subtle adverse effects on reasoning may not be ful recovered in the case of overt hypothyroidism Poorer cognitive outcomes have been linked to clinical hyperthyroidism and greater free thyroxine (FT4) levels with the appropriate scale. For suriety causation and controller the assessment of profits vs hazards of treatments in the growing number of elder persons with medical thyroid illness, more research, including randomised controlled trials, is needed [21][22][23][24][25].…”

Section: Resultsmentioning

confidence: 99%

Effects of Hypothyroidism on Women

Shinde

Paunikar

2021

JPRI

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Background: To determine the impact of treating clinical hypothyroidism during gestation on maternal depressive symptoms. Methods: Females with singleton pregnancies identified clinical hypothyroidism were randomised to prenatal thyroxine medication or sample in an auxiliary study to a multicenter trial. At the end of the pregnancy, the treatment was stopped. Females with overt thyroid disorder, diabetes, autoimmune disorder, or depression were excluded from the study. Before taking the survey medicine (between 3-4 months of pregnancy), between 32 and 38 weeks of pregnancy, and at one year post-delivery, contestants were examined for forbidding symptoms with the help of the Center for Epidemiological Studies-Anxiety zone(CES-D). The primary result was a score on the CES-D for mother depressive symptoms. Results: In individuals with schizophrenia spectrum disorders, imbalanced thyroid hormonal state in general, as well as hypothyroidism and hyperthyroidism, were found in 29.3, 25.17, and 4.08 percent, respectively. These figures were similar to those seen in patients with mental abnormalities (23.24, 21.62 and 1.62 percent, respectively). Anti TPO positivity was found in 11 of the 18 patients with schizophrenia scale illness. There were no distinctions based on gender. Conclusions: Patients with schizophrenia-spectrum disease and mood swings both had thyroid abnormalities. Patients with schizophrenia-spectrum abnormalities were more probably to have autoimmune thyroid disease than those with mood swings. The results highlight the importance of evaluating individuals with schizophrenia-scale abnormalities for thyroid hormone abnormalities and how it affects hypothyroidism.

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Section: Resultsmentioning

confidence: 99%

Effects of Hypothyroidism on Women

Shinde

Paunikar

2021

JPRI

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“…Our case was essentially important as hyperthyroidism, which was probably precipitated by pregnancy, had serious manifestation in the form of HPP. Although hyperthyroid has been reported previously to cause paralysis, this case was exceptional as it was linked with pregnancy and hyperemesis gravidarum, which is rare [ 8 ]. This paralysis required mechanical ventilation and ultimately caused the intrauterine demise.…”

Section: Discussionmentioning

confidence: 99%

Hyperemesis Gravidarum Presenting as Severe Hypokalemic Periodic Paralysis and Type II Respiratory Failure: A Different Form of Thyroid Storm?

Naik¹,

Talwar²,

Acharya³

et al. 2021

Cureus

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Hyperthyroidism in pregnancy is a condition that results from an excess of beta-human chorionic gonadotropin hormone resulting in gestational thyrotoxicosis. This thyrotoxicosis of pregnancy might be linked with hyperemesis gravidarum and is usually a self-limiting disease. Hyperthyroidism can cause hypokalemic periodic paralysis, which presents as pure motor areflexic flaccid paralysis. In severe cases, it may involve respiratory muscles and cause hypercapnic respiratory failure requiring invasive ventilation. A positive feed-forward cycle of hypokalemia could be triggered by the loss of function of inward rectifier potassium channel 18 (Kir2.6) along with the increased activity of sodium, potassium-adenosine triphosphatase (Na⁺/K⁺-ATPase). Hyperthyroid periodic paralysis is characterized by biochemical hyperthyroidism, normal urine potassium excretion, and electrocardiography abnormalities. We report a case of a 23-year-old female (G2P0L0A1) who had severe hyperemesis gravidarum and later on developed flaccid quadriplegia. Her thyroid profile revealed hyperthyroidism. She later developed hypercapnic respiratory failure and was managed by potassium replacement and invasive ventilation.

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“…Few of the related studies were reported by Talwar et. al [11], Somani et al [12], Dixit et al [13]. Kolli et al reported on correlation of thyroid disorders with abnormal uterine bleeding [14].…”

Section: Discussionmentioning

confidence: 99%

Report on Steroid- Responsive Encephalopathy in a Case of Hashimoto’s Thyroiditis

Dehane

Shingode

Patil

2021

JPRI

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Introduction: Thyroiditis caused by Hashimoto's common, Thyroid gland enlargement that is painless and diffuse that affects mostly women in their forties and fifties. While most patients are euthyroid, hypothyroidism may grow. In addition, several patients have thyroid antigen-specific cell-mediated immunity, which can be demonstrated using a variety of strategies. The annual number of cases per 10,000 people prevalence of at least 2% among women. Thyroiditis causes the thyroid gland to become extinct capacity to keep iodine in a safe place, generate together with secrete circulating iodoproteins in the blood, and produce inefficient hormone. As a result, the thyroid gland is overstimulated, and the patient has a high rate of Iodine in the thyroid turnover. Clinical Finding: enlargement of thyroid gland. Difficulty in swallowingand breathing, unexplained weight gain,constipation, slow heart beat, fatigue, swelling in extremities, dryness. Medical History: In 2010 she was suffering from same problems. Hashimoto thyroiditis cured for medical intervention in Nagpur medical college, after that treatment of Hashimoto thyroiditis she took the treatment in A.V.B. R. Hospitalfor management of Hashimoto thyroiditis. Now she is admitted in peadiatrics ward for further management of Hashimoto thyroiditis. The Diagnosis and Therapeutic Intervention: After physical examination and investigation, this case was diagnosed as Hashimoto thyroiditis. Thyroid hormone replacement therapy was used to treat the condition. This normally entails taking levothyroxine. Leoxyl Check: After six to eight weeks of treatment, the TSH level should be normal with dose 12.5-25 mcg. Absorption of levothyroxin may be affected by some drugs, supplements, and diets taken 4 hours. Triiodothyronine 5 to 10 mcg received in twice in day. Nursing Perspectives: Assessement of anterior or posterior location of the thyroid IV Fluid was provided. Check blood pressure and vital signs per hourly. Monitor the Pulse oximetry, ABG, and respiratory rate, and pattern are all factors to consider. Conclusion: Comprehensive systemic review of autoimmune disease, our best estimate of incidence rates for hypothyroidism in female and male treatment and management improves the outcomes of Hashimoto thyroiditis.

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Sub Clinical Disease Presenting with Serious Clinical Manifestations - Blame Thyroid

Cited by 10 publications

References 4 publications

Effects of Hypothyroidism on Women

Effects of Hypothyroidism on Women

Hyperemesis Gravidarum Presenting as Severe Hypokalemic Periodic Paralysis and Type II Respiratory Failure: A Different Form of Thyroid Storm?

Report on Steroid- Responsive Encephalopathy in a Case of Hashimoto’s Thyroiditis

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