Sub-nL thin-film differential scanning calorimetry chip for rapid thermal analysis of liquid samples

Ni, Sheng Huoo; Zhu, Hanliang; Neužil, Pavel; Yobaş, Levent

doi:10.1039/d2lc01094a

Lab Chip

2023

DOI: 10.1039/d2lc01094a

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Sub-nL thin-film differential scanning calorimetry chip for rapid thermal analysis of liquid samples

Sheng Huoo Ni

Hanliang Zhu

Pavel Neužil

et al.

Abstract: Differential scanning calorimetry (DSC) is a popular thermal analysis technique. The miniaturization of DSC on chip as thin-film DSC (tfDSC) has been pioneered for the analysis of ultrathin polymer films...

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2024

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Cited by 2 publications

References 38 publications

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Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis

Zhu,

Xu,

Zhang

et al. 2024

Advanced Science

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The precise measurement of cell temperature and an in‐depth understanding of thermogenic processes are critical in unraveling the complexities of cellular metabolism and its implications for health and disease. This review focuses on the mechanisms of local temperature generation within cells and the array of methods developed for accurate temperature assessment. The contact and noncontact techniques are introduced, including infrared thermography, fluorescence thermometry, and other innovative approaches to localized temperature measurement. The role of thermogenesis in cellular metabolism, highlighting the integral function of temperature regulation in cellular processes, environmental adaptation, and the implications of thermogenic dysregulation in diseases such as metabolic disorders and cancer are further discussed. The challenges and limitations in this field are critically analyzed while technological advancements and future directions are proposed to overcome these barriers. This review aims to provide a consolidated resource for current methodologies, stimulate discussion on the limitations and challenges, and inspire future innovations in the study of cellular thermodynamics.

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Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis

Zhu,

Xu,

Zhang

et al. 2024

Advanced Science

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show abstract

Concurrent determination of heat and capacity change of a sessile droplet using a single measurement

Zhu,

Lu,

Zhang

et al. 2024

Sensors and Actuators A: Physical

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Sub-nL thin-film differential scanning calorimetry chip for rapid thermal analysis of liquid samples

Abstract: Differential scanning calorimetry (DSC) is a popular thermal analysis technique. The miniaturization of DSC on chip as thin-film DSC (tfDSC) has been pioneered for the analysis of ultrathin polymer films...

Cited by 2 publications

References 38 publications

Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis

Exploring the Frontiers of Cell Temperature Measurement and Thermogenesis

Concurrent determination of heat and capacity change of a sessile droplet using a single measurement

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