Subacute bacterial endocarditis caused by Cardiobacterium hominis: A case report

Abstract

Cardiobacterium hominis is a fastidious organism that can rarely cause subacute bacterial endocarditis. This report describes a case involving a 47-year-old man with subacute endocarditis due to C hominis; the isolate was initally found to be resistant to third-generation cephalosporins, but was later found to be susceptible using an alternative method. The authors discuss the likely cause of this error and emphasize the importance of adherence to fully validated methods for the determination of antibiotic susceptibilities.

Difficile examen direct par coloration de Gram : à propos d’un cas d’endocardite à Cardiobacterium hominis et revue de la littérature

“…Two species of Cardiobacterium can currently be described: C. hominis and C. valvarum. criteria of IE [7,8]. Ventricular septal defect, presented by our patient, corresponds to a failure of the inter-ventricular septum and is a congenital heart defect driving to an increased volume load, excessive pulmonary blood flow, reduced systemic cardiac outputs and high pulmonary artery pressure.…”

Cardiobacterium hominis endocarditis associated with cerebral, renal, and splenic infarctions: A case report and review of the literature

“…C. hominis is also known to cause large friable vegetations complicated by systemic embolism [11] . Therefore, we reviewed cases of systemic embolism caused by C. hominis IE ( Table 2 ) [5] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] . 21 cases of C. hominis IE associated with embolism, including the present case, have been reported since 1980.…”

Cardiobacterium hominis and endocarditis. Rare but important clinical relevance

“…Furthermore alternative diagnostic tools such as rt-PCR (real-time polymerase chain reaction) can be used for its identifi cation. Another factor complicating diagnosis of CHIE is that its clinical course is often subacute [2]. This insidious onset explain because diagnosis is made only in more advanced stages, with very large vegetations and peripheral and central nervous system embolization.…”

“…The incidence of Gram-negative endocarditis ranges from 1.3% to 10% and, between them, those ones of the HACEK group are the main causes of these infrequent cases. The "HACEK" acronym represents the fi ve species of microorganisms implicated in these infections, including Haemophilus spp., Aggregatibacter spp., Cardiobacterium hominis (CH), Eikenella corrodens a Kingella kingae [1][2][3].…”