Subacute cutaneous lupus erythematosus associated with breast carcinoma

Paraneoplastic subacute cutaneous lupus erythematosus associated with cholangiocarcinoma

“…In most cases of p‐SCLE the rash precedes the tumour diagnoses. The underlying tumours have been lung, breast, gastric, hepatocellular, non‐Hodgkin lymphoma, laryngeal, uterine and oesophageal adenocarcinoma in situ , but this is the first time SCLE has been linked to cholangiocarcinoma . Paraneoplastic SCLE has been described in relation to cancers of different stages.…”

Subacute cutaneous lupus erythematosus with a possible paraneoplastic association with melanoma

“…Cases are described that completely or partially satisfy McLean’s criteria—with simultaneous onset of SCLE and malignancy, remission of the SCLE when the malignancy is treated, and relapse of both diseases concurrently 1–6. The most common malignancies associated with paraneoplastic SCLE seem to be lung and breast cancer, but numerous other cancers have been implicated 2–17. It appears that most cases present similar to idiopathic SCLE, and most are anti-Ro antibody positive 2–17.…”

“…The most common malignancies associated with paraneoplastic SCLE seem to be lung and breast cancer, but numerous other cancers have been implicated 2–17. It appears that most cases present similar to idiopathic SCLE, and most are anti-Ro antibody positive 2–17. In addition to treating the underlying malignancy, treatment approaches similar to those for idiopathic forms of cutaneous lupus can be used.…”

“…Subacute cutaneous lupus erythematosus (SCLE) can rarely be a paraneoplastic phenomenon, appearing simultaneously with the onset of a cancer, resolving with successful cancer treatment and relapsing with recurrence of the malignancy, thus fulfilling McLean’s criteria for paraneoplastic dermatoses 1–6. While paraneoplastic SCLE is reported in association with many cancers, breast and lung cancer are the most commonly implicated malignancies 2–17. SCLE can be drug-induced, and proton pump inhibitors (PPIs) may be among the most common culprit medications 18 19…”

Drug-induced subacute cutaneous lupus erythematosus associated with docetaxel chemotherapy: a case report

“…Although SCLE is classically characterized as either idiopathic or drug-induced, there has been sufficient evidence in the literature to consider certain cases of SCLE to have a paraneoplastic etiology [ 19 ]. There have been multiple reports of SCLE arising in the setting of internal malignancy including two cases in breast adenocarcinomas [ 20 ]. Like other paraneoplastic dermatoses, presentations of paraneoplastic SCLE follow the criteria in that the cutaneous findings appear temporally after development of the malignancy, and their clinical courses typically run parallel [ 21 ].…”