Subacute Disseminated Mucormycosis in a Diabetic Male

Nolan, Robert L.; Carter, Ralph R.; Griffith, James; Chapman, Stanley W.

doi:10.1097/00000441-198910000-00008

Cited by 11 publications

(6 citation statements)

References 6 publications

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“…Subacute (> 4–6 weeks of symptoms) pulmonary, and even disseminated mucormycosis, cases in diabetic patients have been reported [47,89]. Lee et al .…”

Section: Pulmonarymentioning

confidence: 99%

“…Patients can present with cough, fever, haemoptysis and ⁄ or pleuritic chest pain [5,11,87]. Leukocytosis need not be present [11,89]. Haematology patients can have coexisting infection with Aspergillus species, Candida species, bacteria, or cytomegalovirus [5,11,19,21].…”

Section: Rhino-orbital-cerebralmentioning

confidence: 99%

“…Subacute (> 4-6 weeks of symptoms) pulmonary, and even disseminated mucormycosis, cases in diabetic patients have been reported [47,89]. Lee et al found that 18% of pulmonary mucormycosis cases had symptoms for > 30 days [11].…”

Section: Rhino-orbital-cerebralmentioning

confidence: 99%

“…Disseminated mucormycosis involves two or more noncontiguous organs. Neutropenic patients with leukaemia or lymphoma comprise the majority of patients with disseminated mucormycosis [4,89]. Dissemination occurs in 23-62% of cases with haematological malignancy [3,4,6,19,22,117].…”

Section: Disseminatedmentioning

confidence: 99%

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Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment

Prabhu

Patel

2004

Clinical Microbiology and Infection

502

422

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The class Zygomycetes is divided into two orders, Mucorales and Entomophthorales. These two orders produce dramatically different infections. Genera from the order Mucorales (Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Cunninghamella and Saksenaea) cause an angioinvasive infection called mucormycosis. Mucormycosis presents with rhino-orbito-cerebral, pulmonary, disseminated, cutaneous, or gastrointestinal involvement. Immunocompromising states such as haematological malignancy, bone marrow or peripheral blood stem cell transplantation, neutropenia, solid organ transplantation, diabetes mellitus with or without ketoacidosis, corticosteroids, and deferoxamine therapy for iron overload predispose patients to infection. Mucormycosis in immunocompetent hosts is rare, and is often related to trauma. Mortality rates can approach 100% depending on the patient's underlying disease and form of mucormycosis. Early diagnosis, along with treatment of the underlying medical condition, surgery, and an amphotericin B product are needed for a successful outcome. Genera from the order Entomophthorales produce a chronic subcutaneous infection called entomophthoramycosis in immunocompetent patients. This infection occurs in tropical and subtropical climates. The genus Basidiobolus typically produces a chronic subcutaneous infection of the thigh, buttock, and/or trunk. Rarely, it has been reported to involve the gastrointestinal tract. The genus Conidiobolus causes a chronic infection of the nasal submucosa and subcutaneous tissue of the nose and face. This paper will review the clinical manifestations, diagnosis and treatment of mucormycosis and entomophthoramycosis.

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“…Subacute (> 4–6 weeks of symptoms) pulmonary, and even disseminated mucormycosis, cases in diabetic patients have been reported [47,89]. Lee et al .…”

Section: Pulmonarymentioning

confidence: 99%

Section: Rhino-orbital-cerebralmentioning

confidence: 99%

Section: Rhino-orbital-cerebralmentioning

confidence: 99%

Section: Disseminatedmentioning

confidence: 99%

See 2 more Smart Citations

Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment

Prabhu

Patel

2004

Clinical Microbiology and Infection

502

422

View full text Add to dashboard Cite

show abstract

“…Rhinocerebral disease is the most common manifestation, but pulmonary, cutaneous, gastrointestinal, and widely disseminated forms have been reported. [2][3][4][5] In this case, the fungus was present within the blood stream and had attached to blood vessels with proliferation, causing local thrombosis. This was not an embolic phenomenon.…”

Section: Discussionmentioning

confidence: 99%

Intravascular mucormycosis as a cause of arm ischemia in an immunocompromised patient

Sochaj

Claridge

Green

et al. 2009

Journal of Vascular Surgery

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Mucormycosis is an opportunistic fungal infection primarily affecting patients with immunosuppression. We present a case of upper limb ischemia secondary to mucormycosis. A 59-year-old man with myelodysplasia presented with an acutely ischemic arm. The patient underwent numerous revascularisation attempts. Following the final procedure, he developed a cerebral infarct and subsequently died. The most common presentations of mucormycosis are of local character. Once established, it can spread rapidly with vascular invasion and in situ thrombosis. Mortality rate is 76%-96%. In this case, it led to fulminant intravascular coagulopathy resulting in recurrent upper and lower limb ischemia, and finally cerebral infarction.

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Chronic Infections of the Small Intestine

Bourke¹,

Hussey²

2015

Yamada' S Textbook of Gastroenterology

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Subacute Disseminated Mucormycosis in a Diabetic Male

Cited by 11 publications

References 6 publications

Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment

Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment

Intravascular mucormycosis as a cause of arm ischemia in an immunocompromised patient

Chronic Infections of the Small Intestine

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