Subacute thyroiditis

Ayesa, Sally

doi:10.53347/rid-80277

Cited by 4 publications

(4 citation statements)

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“…The condition manifests as hyperthyroidism during the initial 4–6 weeks followed by hypothyroidism lasting for another 6–12 weeks. Patients often become euthyroid after 12–15 weeks [6]. It is difficult to distinguish post vaccine‐SAT from post‐infection SAT clinically and biochemically and only minor differences exist between the two [7].…”

Section: Discussionmentioning

confidence: 99%

Patterns and outcomes of late onset thyroid disturbances after COVID‐19 vaccination: A report of 75 cases

Kaur,

Reddy,

Reddy

et al. 2023

Tropical Med Int Health

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Isolated cases of subacute thyroiditis exist in the early period of COVID‐19 vaccination, largely after mRNA vaccines. Here we report late onset thyroid disturbances and persistent health issues in patients of thyroid disorders after COVID‐19 vaccination. Seventy‐five patients with post COVID‐19 vaccination thyroid disturbances were identified. Among these, 41 had flare of underlying thyroid illness, majority occurring at a median time lag of 28.4 weeks since 2nd dose. Thirty‐one cases of new onset hypothyroidism and three of new onset hyperthyroidism were reported, with a median time lag respectively of 17.2 and 22.6 weeks since 2nd dose. Most cases occurred after ChAdOx1‐nCoV‐19, which was the commonest vaccine employed in mass roll out in India. Significant improvement was observed in majority, after a median follow up of 22–26 weeks. New onset health issues persisting for ≥4 weeks were reported in 37.3% and were common in individuals with history of COVID‐19 before vaccine. New onset metabolic, musculoskeletal, and reproductive disorders were the common health complaints. Active monitoring is warranted for late onset adverse events after COVID‐19 vaccines of all types. Larger studies with involvement of unvaccinated individuals are required to understand the incidence and causality of late onset thyroid disturbances after COVID‐19 vaccines.

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Section: Discussionmentioning

confidence: 99%

Patterns and outcomes of late onset thyroid disturbances after COVID‐19 vaccination: A report of 75 cases

Kaur,

Reddy,

Reddy

et al. 2023

Tropical Med Int Health

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“…Laboratory studies reveal suppressed levels of TSH, elevated T3 and T4 levels, as well as increased WBC, CRP, and ESR levels. While anti‐thyroid peroxidase antibodies (Anti‐TPO) are typically found in painless SAT, they are usually absent or present in low titers in painful SAT 3 . Thyroid scintigraphy evaluates the iodine‐123 iodide or 99m Tc‐pertechnetate uptake and distribution, which is expected to be markedly reduced in SAT 4,5 …”

Section: Introductionmentioning

confidence: 99%

Subacute thyroiditis after SARS‐CoV‐2 vaccination: A case report

Akha,

Mazandarani,

Azari

et al. 2024

Clinical Case Reports

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Key Clinical MessageSubacute thyroiditis which is typically characterized by cervical pain and fever is caused by viral infection and is seen after SARS‐CoV‐2 vaccination. Here we report a post‐vaccination subacute thyroiditis after SARS‐CoV‐2 vaccination.AbstractSubacute thyroiditis (SAT) is possibly caused by a viral infection and is typically characterized by cervical pain and fever. SAT associated with SARS‐CoV‐2 infection or SARS‐CoV‐2 vaccination has been reported, albeit in limited numbers. A 34‐year‐old woman was referred to our clinic with typical SAT symptoms. The diagnosis was confirmed through thyroid scintigraphy after receiving the SARS‐CoV‐2 vaccination, despite testing negative for COVID‐19 via RT‐PCR. There is a theoretical correlation between SARS‐CoV‐2 vaccination and SAT. Vaccination may have a direct or indirect impact on the thyroid, but further studies are required to confirm this relationship. A systematic review of the literature of similar cases was performed for comparison. Ultimately, the overall benefits of SARS‐CoV‐2 vaccination outweigh the potential adverse effects. Therefore, these types of reports should not divert attention from the actual reality.

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“…Subacute thyroiditis tends to present with pain in the anterior neck followed by upper respiratory tract infection or sore throat and is postulated as being caused by viral infection. Inflammatory symptoms, such as nodular or diffuse enlargement of the goiter with spontaneous pain, tenderness and a fever, are also seen, as are symptoms of thyrotoxicosis, such as palpitations ( 5 ). Echography shows an indistinct hypoechoic area with reduced blood flow signals, in line with the induration, enlargement or pain, and in about 60% of cases, enlarged lymph nodes around the thyroid gland are reported ( 6 ) It is rare in children and the elderly ( 7 ), and most cases heal within a few months, although about 20% relapse during recovery ( 8 , 9 ), and 15% develop permanent hypothyroidism ( 9 ).…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Painless Destructive Thyroiditis Resulting in Thyroid Storm

et al. 2023

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Thyroid storm is a life-threatening clinical condition that is usually triggered by untreated or interrupted treatment of Graves' disease, leading to the sudden onset of severe thyrotoxicosis, which requires an immediate diagnosis and treatment based on diagnostic criteria. Cases of thyroid storm caused by painless/painless subacute thyroiditis are very rare. We herein report an 85-year-old man with features of severe thyrotoxicosis caused by painless/painless subacute thyroiditis who had no uptake of 99m TcO4 and was negative for thyroidstimulating hormone receptor antibodies. In thyroid storm patients in whom the findings are inconsistent with Graves' disease, careful follow-up and management are necessary, assuming the possibility of painless or painless subacute thyroiditis.

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Subacute thyroiditis

Cited by 4 publications

References 0 publications

Patterns and outcomes of late onset thyroid disturbances after COVID‐19 vaccination: A report of 75 cases

Patterns and outcomes of late onset thyroid disturbances after COVID‐19 vaccination: A report of 75 cases

Subacute thyroiditis after SARS‐CoV‐2 vaccination: A case report

A Rare Case of Painless Destructive Thyroiditis Resulting in Thyroid Storm

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