Subcellular distribution of zinc and cadmium in the hepatopancreas and gills of the decapod crustacean Penaeus indicus

Núñez-Nogueira, Gabriel; Mouneyrac, Catherine; Amiard, J. C.; Rainbow, P. S.

doi:10.1007/s00227-006-0350-0

Cited by 22 publications

(23 citation statements)

References 41 publications

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“…Their ultrastructure clearly indicates that they are synthetically active, absorb material from the tubular lumen, accumulate material in the central vacuole, and discharge this vacuole in a late phase of the digestive cycle. The central vacuole in metal contaminated decapods occasionally contained smaller amounts of metals (e.g., Nunez‐Nogueira et al, ), but it is unlikely that this reflects a regular detoxification mechanism. B‐cells may rather have absorbed the metals from the tubular lumen together with other endocytosed stuff.…”

Section: Discussionmentioning

confidence: 99%

“…Some heavy metals, for example, cadmium, are detoxified in the hepatopancreas, but are not deposited in granules. They are rather bound to cytoplasmic metallothioneins as shown for shrimp Penaeus indicus H. Milne Edwards, 1837 (Nunez‐Nogueira et al, ) and crayfish Procambarus clarkii (Girard, 1852) (Del Ramo et al, ). This mode of detoxification is not visible with microscopic techniques, and therefore, the involved cell type is not yet identified, but it is probably the R‐cell as well.…”

Section: Detoxification Of Xenobiotics In Epithelial Cellsmentioning

confidence: 98%

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Functional cytology of the hepatopancreas of decapod crustaceans

Vogt

2019

Journal of Morphology

178

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This article reviews the morphogenesis, morphology, histology, ultrastructure, and structural-functional relationships of the hepatopancreas, the main metabolic organ of the Decapoda. The hepatopancreas develops in early larval stages from a pair of lateral lobes of the midgut anlage. In adults, it consists of hundreds of blindly ending tubules that are enveloped by a muscle net consisting of longitudinal and circular fibers. Stem cells at the distal ends of the tubules give rise to three ultrastructurally different epithelial cell types, the R-, F-, and B-cells. Histochemistry, immunohistochemistry, in situ hybridization, and monitoring of ultrastructural changes under different experimental conditions allowed the attribution of functions to these cell types. R-cells serve for the absorption and metabolization of nutrients, storage of energy reserves and minerals, synthesis of lipoproteins for export to other organs, detoxification of heavy metals, and excretion of uric acid. F-cells synthesize digestive enzymes and blood proteins involved in oxygen transport and immune defense. They also detoxify some heavy metals and probably organic xenobiotics. B-cells are assumed to produce and recycle fat emulsifiers. The hepatopancreas tubules lack nerves. The presence of scattered M-cells with putative endocrine function in the epithelium suggests that the hepatopancreas is mainly hormonally controlled. M-cells probably represent a self-perpetuating cell lineage independent from E-cells. The interstitium between the tubules contains connective tissue, arterioles, hemolymph with circulating hemocytes, and fixed phagocytes that eliminate pathogens.The hepatopancreas is histologically and ultrastructurally uniform throughout the Decapoda, despite their broad variety in body size, morphology, life style, and ecology.However, in a few cavernicolous and deep-sea shrimps parts of the hepatopancreas are transformed into large oil storing and bioluminescent compartments. Within the malacostracan crustaceans, the hepatopancreas of the Decapoda is most similar to the digestive gland of the Euphausiacea, supporting close taxonomic relationship of these two taxa.

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Section: Discussionmentioning

confidence: 99%

Section: Detoxification Of Xenobiotics In Epithelial Cellsmentioning

confidence: 98%

Functional cytology of the hepatopancreas of decapod crustaceans

Vogt

2019

Journal of Morphology

178

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“…The damage caused by Cd could be due to reduced protein synthesis in the hepatocytes because of the cytotoxic effect of this metal (Wu and Chen, 2005), which is known to induce cell necrosis and accelerated apoptosis of cells of the immune system (Wang et al, 2013), while in the case of the Zninduced hepatopancreatic damage, the effect could be due to accelerated excretion through sloughing towards the lumen of metal-overloaded cells (Nuñez-Nogueira et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

Untitled

Frías-Espericueta¹,

Abad‐Rosales²,

Vargas-Jimenez³

et al. 2016

Turk. J. Fish. Aquat. Sci.

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Litopenaeus vannamei postlarvae were exposed during 4 weeks to progressively increasing sublethal concentrations of cadmium and zinc (Cd: 8.8, 24, Zn: 81, 160, ), used alone or in mixture, in order to evaluate their joint effect on survival and growth, and on the histological structure of hepatopancreas and gills of the exposed organisms. After exposure to single metals there were no differences between control and treatments in survival and growth, while survival was significantly lower with the highest concentration of the mixture. Growth was also affected and showed a significant dose-related response. No histopathologies were observed in gills of shrimps exposed to single metals, while their hepatopancreas showed moderate to severe changes during the first three weeks. With the mixture, moderate edemas were present in gills lacunae and the hepatopancreas had sloughing of epithelial cells until the third week, but no histological alterations were evident by the end of the experiment. The results of this study show a synergistic effect of the mixture Cd + Zn on survival, growth and histological structure of hepatopancreas and gills of the Pacific white shrimp L. vannamei.

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“…The relationship of metals with maturity in marine mammals has been observed in other elements such as Cd and Hg in cetaceans and pinnipeds [116]. These three elements are considered non-essential, so their bioaccumulation depending on the amount of exposure and maturity might be related to lower excretion rates than essential elements as they have been in aquatic animals [117,118,119,120] and this could be the cause of their greater presence in older individuals exposed to lead during their longer lifespan.…”

Section: Trace Elements Reported In Sireniamentioning

confidence: 99%

As, Cr, Hg, Pb, and Cd Concentrations and Bioaccumulation in the Dugong Dugong dugon and Manatee Trichechus manatus: A Review of Body Burdens and Distribution

Núñez-Nogueira

Pérez-López

Santos-Córdova

2019

IJERPH

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The death of dozens of manatees Trichechus manatus recently in Tabasco, Mexico, has captured international attention. Speculation about possible causes include water and food contamination by metals. Although federal authorities have ruled out water chemical pollution, the cause of these deaths is still awaiting conclusive laboratory results. Present work seeks to summarize information currently available on non-essential metals and those of great toxicological relevance in Sirenia (dugongs and manatees), highlighting its body distribution, presence in blood, and its relationship with their geographical distribution, gender and age, whenever possible. This paper focuses on the five elements: As, Cr, Hg, Pb and Cd, which are commonly considered as threats for marine mammals and reported in Sirenia. Some of these metals (Cr and Cd) were thought to be related to the recent deaths in Tabasco. All five elements are accumulated by Sirenia at different levels. Metal presence is associated to their diet but does not necessarily imply adverse effects for dugongs and manatees. Toxicological aspects and the human consumption risk in case of any illegal or traditional consumption in some cultures are discussed. Important toxicological research areas that need to be addressed are highlighted.

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Subcellular distribution of zinc and cadmium in the hepatopancreas and gills of the decapod crustacean Penaeus indicus

Cited by 22 publications

References 41 publications

Functional cytology of the hepatopancreas of decapod crustaceans

Functional cytology of the hepatopancreas of decapod crustaceans

Untitled

As, Cr, Hg, Pb, and Cd Concentrations and Bioaccumulation in the Dugong Dugong dugon and Manatee Trichechus manatus: A Review of Body Burdens and Distribution

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