Subclinical Myocardial Injury of Young Patients With Type1 Diabetes Mellitus Without Cardiovascular Disease

Abstract

The aim: to study the impact of Type1 Diabetes mellitus (DM) on systolic function of left ventricle (LV) of young patients without cardiovascular disease (CVD) and identify factors associated with dysfunction of global longitudinal systolic deformation. Young patients with Type1 DM (N=71) and without CVD were included in the study. Mean age was 28,7 years, 57% men, glycated hemoglobin 9,9%, body mass index 23,4 kg/m2, and diabetes duration 6,84 [0,5; 24], NT-proBNP 62,62 pg/ml, LV EF 61,7%. Treadmill test was conducted to all patients in order to exclude coronary disease.