Subcutaneous Gammanorm® by pump or rapid push infusion: Impact of the device on quality of life in adult patients with primary immunodeficiencies

Warnatz, Klaus; Jolles, Stephen; Agostini, Carlo; Vianello, Fabrizio; Borte, Michael; Bethune, Claire; Grigoriadou, Sofia; Richter, Alex; Jain, Rashmi; Lowe, David M.; Katelaris, Constance H.; Milito, Cinzia; Cook, Matthew

doi:10.1016/j.clim.2022.108938

Cited by 4 publications

(1 citation statement)

References 22 publications

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“…When this was not possible, home-based IVIg administered via Immunology Clinical Nurse Specialists was undertaken. Rapid push SCIg can be administered via a needle and syringe using smaller and more frequent doses (taking approximately 5–20 min) than traditional weekly infusion pump administered SCIg [17,18 ▪ ]. Due to its relative simplicity, transition to rapid push SCIg was selected as the most efficient manner to support rapid shielding whilst ensuring continued access to IgRT.…”

Section: Introductionmentioning

confidence: 99%

Immunodeficient patient experience of emergency switch from intravenous to rapid push subcutaneous immunoglobulin replacement therapy during coronavirus disease 2019 shielding

Morgan

Jolles

Ponsford

et al. 2022

Current Opinion in Allergy &Amp; Clinical Immunology

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Purpose of reviewWelsh immunodeficient patients on immunoglobulin replacement therapy (IgRT) who were considered high risk for severe coronavirus disease 2019 (COVID-19) were directed to shield. Consequently, patients receiving hospital-based intravenous immunoglobulin (IVIg) quickly transitioned to home-based selfadministered subcutaneous immunoglobulin (SCIg). This evaluation aimed to assess patients' perceptions and experiences and laboratory outcomes of emergency IgRT transition during COVID-19. Recent findingsA quick transition from in-hospital IVIg to home-based rapid push SCIg is achievable, however, patient IgRT administration preference remains key outside of emergency shielding measures.

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Section: Introductionmentioning

confidence: 99%