Subcutaneous Mastectomy with Lymphadenectomy and Irradiation for Primary Treatment of Breast Cancer

Beller, F. K.; Schmidt, Eva

doi:10.1007/978-3-642-70192-4_32

Cited by 2 publications

(1 citation statement)

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“…There is substantial evidence that the technique of subcutaneous mastectomy leaves breast tissue behind, and the desired effect of cancer prophylaxis cannot be achieved. In performing subcutaneous mastectomies, Heller has added postoperative irradiation, reducing the incidence of recurrence to an acceptable level of 1% [34]. Moreover, in several series, subcutaneous mastectomy is associated with an unacceptable rate of surgical complications.…”

Section: Prophylactic Contralateral Mastectomymentioning

confidence: 99%

Bilateral breast cancer

Fracchia

Borgen

1991

Seminars in Surgical Oncology

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Bilateral breast cancer has a cumulative incidence of 7% to 20% in patients with primary operable breast cancer, and the majority of these lesions are metachronous. A consensus on the management of the contralateral breast has been elusive. Much of the confusion arises from the fact that there exist marked differences of opinion regarding the impact of a second primary breast cancer on the overall prognosis. The risk of developing a contralateral breast cancer is influenced by the age of the patient, the presence of in situ disease, lobular histology of this new lesion, multicentricity, exposure to certain types of ionizing irradiation, and, possibly, family history of breast cancer. Management options include observation (clinical and mammographic surveillance), contralateral biopsy, and, rarely, prophylactic mastectomy. It is hoped that trials of breast cancer prevention, employing drugs such as tamoxifen, will identify agents capable of abrogating the risk of contralateral breast cancer and improve the ultimate outcome.

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Section: Prophylactic Contralateral Mastectomymentioning

confidence: 99%