Subcutaneous power supply by NIR-II light

Abstract

Implantable medical devices are wished to be recharged via contactless power transfer technologies without interventional operations. Superior to subcutaneous power supply by visible light or electromagnetic wave, second near-infrared (NIR-II) light is predicted to possess 60 times subcutaneous power transmission but hard to be utilized. Here we report a photo-thermal-electric converter via the combination of photothermal conversion and thermoelectric conversion. It is able to generate an output power as high as 195 mW under the coverage of excised tissues, presenting advantages of non-invasion, high output power, negligible biological damage, and deep tissue penetration. As an in vivo demonstration, the output power of a packaged converter in the abdominal cavity of a rabbit reaches 20 mW under NIR-II light irradiation through the rabbit skin with a thickness of 8.5 mm. This value is high enough to recharge an implanted high-power-consumption wireless camera and transfer video signal out of body in real-time.

Pt(iv) anticancer prodrugs bearing an oxaliplatin scaffold: what do we know about their bioactivity?

“…134 NIR-II light has been recognized to be a window of biological transparency and exhibits a much deeper penetration through skin tissues than other wavelengths. 135 What is more, organic photothermal reagents that absorb in the NIR-II region are usually considered to be biosafe and to possess low phototoxicity. 136 In vitro , 101 demonstrated higher toxicities, remarkably under light irradiation, than oxaliplatin in CT26, 143B, OV8 and 4T1 cells associated to a higher Pt intracellular accumulation and immunogenic cell death induction.…”

A Supramolecular Naphthalene Diimide Radical Anion with Efficient NIR‐II Photothermal Conversion for E. coli‐Responsive Photothermal Therapy

“…Near-infrared (NIR) light, owing to decreased photon absorbance and scattering, can effectively penetrate biological tissues such as skin and blood to achieve excellent imaging and therapeutic effects. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] The NIR spectral range, which is known as the biological tissue optical window, usually includes two main regions, NIR-I (650-1000 nm) and NIR-II (1000-1700 nm). [15] Compared with NIR-I light, NIR-II light has enhanced tissue penetration and better radiation tolerance.…”

A Supramolecular Naphthalene Diimide Radical Anion with Efficient NIR‐II Photothermal Conversion for E. coli‐Responsive Photothermal Therapy

“…Near-infrared (NIR) light, owing to decreased photon absorbance and scattering, can effectively penetrate biological tissues such as skin and blood to achieve excellent imaging and therapeutic effects. [1][2][3][4][5][6][7][8][9][10][11][12][13][14] The NIR spectral range, which is known as the biological tissue optical window, usually includes two main regions, NIR-I (650-1000 nm) and NIR-II (1000-1700 nm). [15] Compared with NIR-I light, NIR-II light has enhanced tissue penetration and better radiation tolerance.…”