Subependymal giant cell astrocytoma: a report of five cases

Clinical and imaging features of subependymal giant cell astrocytoma: report of 20 cases

“…Facial angiofibromas were presented in approximately 85% of older children and adolescents. Multiple peri/subungual fibromas, pathognomonic of were seen in 15-20% of cases [19], as seen in our cases that all these 4 patients with facial angiofibroma were over 3 years old.…”

“…The earlier the seizures occured, the poorer was the intellectual outcome of the patient [19]. In present series, 2 patients with epilepsy showed poor intellectual development at the age of 4 months and 3 years respectively.…”

Cytologic Features of Subependymal Giant Cell Astrocytoma

“…2,3 SEGAs usually occur in the setting of tuberous sclerosis complex (TSC), with a reported incidence of ~5-14% in patient with TSC 2,4,5 ; however, there are several reported cases in which patients with this tumor had no other stigmata of TSC. 3,6,7 Of note, SEGA can be detected as an initial manifestation of TSC, 3 and a newly discovered SEGA should prompt careful neurologic and systemic examination for TSC. In order to establish the optimal treatment plan for patients with brain tumors, an intraoperative diagnosis is often necessary.…”

Management of subependymal giant cell tumors in tuberous sclerosis complex: the neurosurgeon’s perspective

“…5): transient hemiparesis (10%-12%), [3,49] permanent motor defi cit (6%-12.5%), [3,10,37] reintervention for hemorrhage or compressive subdural collection (13%-20%). [1,3,57] An acute postoperative fatal hydrocephalus is not a rare event as it may occur in 10% to 20% of cases, generally secondary to infection or hemorrhage. [1,37,57] A postoperative cognitive impairment may also be observed, but problematical to assess as it occurs in …”